FGF basic / FGF2 - DP3506S | acris-antibodies.com

Product Description for FGF basic / FGF2

Rabbit anti Human FGF basic / FGF2.
Presentation: Azide Free
Product is tested for Functional assay, Western blot / Immunoblot.

Properties for FGF basic / FGF2

Product Category	Primary Antibodies
Target Category	FGF basic / FGF2 antibody
Quantity	0.1 mg
Synonyms	BFGF, FGFB, Fibroblast growth factor 2 (basic), HBGF-2, HBGF2, Heparin-binding growth factor 2
Presentation	Azide Free
Reactivity	Hu
Applications	FN, WB
Clonality	Polyclonal
Host	Rabbit
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen	Swiss Prot Num: P09038 Immunogen: Highly pure (> 98%) recombinant Human FGF-2 (basic) [Ala136 – Ser288] produced in E.coli (Cat.-No DA3503XC). GeneID: 2247
Application	Neutralization: To yield one-half maximal inhibition (ND50) of the biological activity of human FGF-2 basic (5 ng/ml) on HUVEC cells, a concentration of about 3.5 µg/ml of this antibody is required. Western Blot: 2-5 µg/ml.
Background	FGF basic (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
General Readings	Coulier F, Pontarotti P, Roubin R, Hartung H, Goldfarb M, Birnbaum D. Of worms and men: an evolutionary perspective on the fibroblast growth factor (FGF) and FGF receptor families. J Mol Evol. 1997 Jan;44(1):43-56. PubMed PMID: 9010135. Fernig DG, Gallagher JT. Fibroblast growth factors and their receptors: an information network controlling tissue growth, morphogenesis and repair. Prog Growth Factor Res. 1994;5(4):353-77. PubMed PMID: 7780086. Presta M, Dell'Era P, Mitola S, Moroni E, Ronca R, Rusnati M. Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. Cytokine Growth Factor Rev. 2005 Apr;16(2):159-78. Epub 2005 Feb 2. PubMed PMID: 15863032. Claus P, Doring F, Gringel S, Muller-Ostermeyer F, Fuhlrott J, Kraft T, et al. Differential intranuclear localization of fibroblast growth factor-2 isoforms and specific interaction with the survival of motoneuron protein. J Biol Chem. 2003 Jan 3;278(1):479-85. Epub 2002 Oct 22. PubMed PMID: 12397076. Quarto N, Fong KD, Longaker MT. Gene profiling of cells expressing different FGF-2 forms. Gene. 2005 Aug 15;356:49-68. PubMed PMID: 16023796. Tsuneto M, Yamazaki H, Yoshino M, Yamada T, Hayashi S. Ascorbic acid promotes osteoclastogenesis from embryonic stem cells. Biochem Biophys Res Commun. 2005 Oct 7;335(4):1239-46. PubMed PMID: 16112648. Hébert JM, Basilico C, Goldfarb M, Haub O, Martin GR. Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis. Dev Biol. 1990 Apr;138(2):454-63. PubMed PMID: 2318343.
Storage	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	Purification: Affinity Chromatography on Protein A Buffer System: PBS, pH 7.4 without stabilizer or preservative State: Lyophilized purified IgG fraction Azide Free Reconstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/ml
Specificity	Specificity: The antibody will detect Human FGF-2 (basic).
Gene ID	2247

Accessory Products

Proteins and/or Positive Controls

Proteins for FGF basic / FGF2 (31 products)

Catalog No.	Species	Pres.	Purity	Source
TP750002	FGF basic / FGF2
	Human		> 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.	E. coli	0.1 mg / $411.00
					OriGene Technologies, Inc.
TP317426	FGF basic / FGF2
	Human		> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.	HEK293 cells	20 µg / $748.00
					OriGene Technologies, Inc.
TP720037	FGF basic / FGF2
	Human		> 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.	E. coli	10 µg / $299.00
					OriGene Technologies, Inc.
TP723109	FGF basic / FGF2
	Human		> 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.	E. coli
					OriGene Technologies, Inc.
TP723110	FGF basic / FGF2
	Human		> 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.	E. coli	50 µg / $230.00
					OriGene Technologies, Inc.
TP723719	FGF basic / FGF2
	Human		> 98 % Preparation: . Purity Detail: Purity is >98%, as determined by Coomassie stained SDS-PAGE.	E. coli	10 µg / $135.00
					OriGene Technologies, Inc.
AR09356PU-L	FGF basic / FGF2 (recombinant)
	Human	Purified	> 95 % Heparin affinity chromatography	E. coli
					OriGene Technologies GmbH
AR09356PU-N	FGF basic / FGF2 (recombinant)
	Human	Purified	> 95 % Heparin affinity chromatography	E. coli
					OriGene Technologies GmbH
AR09356PU-S	FGF basic / FGF2 (recombinant)
	Human	Purified	> 95 % Heparin affinity chromatography	E. coli
					OriGene Technologies GmbH
AR10036PU-L	FGF basic / FGF2
	Human	Purified	>98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.	Insect cells
					OriGene Technologies GmbH
AR10036PU-N	FGF basic / FGF2
	Human	Purified	>98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.	Insect cells
					OriGene Technologies GmbH
AR10036PU-S	FGF basic / FGF2
	Human	Purified	>98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.	Insect cells
					OriGene Technologies GmbH
AR10039PU-L	FGF basic / FGF2 (cell culture grade)
	Human	Purified	> 98.0% as determined by both RP-HPLC and SDS-PAGE analysis. Purification Method: Proprietary chromatographic techniques.	E. coli
					OriGene Technologies GmbH
AR10039PU-N	FGF basic / FGF2 (cell culture grade)
	Human	Purified	> 98.0% as determined by both RP-HPLC and SDS-PAGE analysis. Purification Method: Proprietary chromatographic techniques.	E. coli
					OriGene Technologies GmbH
AR10039PU-S	FGF basic / FGF2 (cell culture grade)
	Human	Purified	> 98.0% as determined by both RP-HPLC and SDS-PAGE analysis. Purification Method: Proprietary chromatographic techniques.	E. coli
					OriGene Technologies GmbH
AR10041PU-L	FGF basic / FGF2 (Animal Product Free Grade)
	Human	Purified	> 95% pure as determined by 10% PAGE (coomassie staining). Purification Method: DEAE sepharose, Affinity Chromatography.	E. coli
					OriGene Technologies GmbH
AR10042PU-L	FGF basic / FGF2 (Stem Cell Grade)
	Human	Purified	> 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.	E. coli
					OriGene Technologies GmbH
AR10042PU-N	FGF basic / FGF2 (Stem Cell Grade)
	Human	Purified	> 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.	E. coli
					OriGene Technologies GmbH
AR10042PU-S	FGF basic / FGF2 (Stem Cell Grade)
	Human	Purified	> 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.	E. coli
					OriGene Technologies GmbH
AR31105PU-N	FGF basic / FGF2 (164 amino acids)
	Human	Purified	> 98 % pure by SDS-PAGE and HPLC analyses	E. coli
					OriGene Technologies GmbH
AR31105PU-S	FGF basic / FGF2 (146 amino acids)
	Human	Purified	> 98 % pure by SDS-PAGE and HPLC analyses	E. coli
					OriGene Technologies GmbH
AR50023PU-N	FGF basic / FGF2 (143-288) (recombinant)
	Human	Purified	> 95 % by SDS - PAGE	E. coli
					OriGene Technologies GmbH
AR50023PU-S	FGF basic / FGF2 (143-288) (recombinant)
	Human	Purified	> 95 % by SDS - PAGE	E. coli
					OriGene Technologies GmbH
DA3503	FGF basic / FGF2
	Human	Purified	> 98 % by SDS-PAGE and visualised by silver stain	E. coli	10 µg / $160.00
					OriGene Technologies GmbH
DA3503X	FGF basic / FGF2
	Human	Purified	> 98 % by SDS-PAGE and visualised by silver stain	E. coli	25 µg / $180.00
					OriGene Technologies GmbH
DA3503XC	FGF basic / FGF2
	Human	Purified	> 98 % by SDS-PAGE and visualised by silver stain	E. coli	50 µg / $240.00
					OriGene Technologies GmbH
PA055	FGF basic / FGF2 (154 amino acids)
	Human	Purified	> 95 % pure by SDS-PAGE and HPLC analyses	E. coli
					OriGene Technologies GmbH
PA055X	FGF basic / FGF2 (154 amino acids)
	Human	Purified	> 95 % pure by SDS-PAGE and HPLC analyses	E. coli
					OriGene Technologies GmbH
PA1015	FGF basic / FGF2
	Human	Purified	> 95 % Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.	Insect cells
					OriGene Technologies GmbH
PA1015X	FGF basic / FGF2
	Human	Purified	> 95 % Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.	Insect cells
					OriGene Technologies GmbH
PA1015XC	FGF basic / FGF2
	Human	Purified	> 95 % Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.	Insect cells
					OriGene Technologies GmbH

Recommended Secondary Antibodies for FGF basic / FGF2 (9 products)

Catalog No.	Host	Pres.	React.	Applications
R1364AP	Rabbit IgG (H+L chain) antibody
	Goat	AP	Rb	E, WB
					OriGene Technologies GmbH
R1364B	Rabbit IgG (H+L chain) antibody
	Goat	Biotin	Rb	E, WB
					OriGene Technologies GmbH
R1364F	Rabbit IgG (H+L chain) antibody
	Goat	FITC	Rb	E, ICC/IF, WB
					OriGene Technologies GmbH
R1364HRP	Rabbit IgG (H+L chain) antibody
	Goat	HRP	Rb	E, P, WB
					OriGene Technologies GmbH
R1364T	Rabbit IgG (H+L chain) antibody
	Goat	TRITC	Rb	E, F, ICC/IF
					OriGene Technologies GmbH
R1427R	Rabbit IgG F(ab)2 Fragment (H+L chain) antibody
	Donkey	PE	Rb	F
					OriGene Technologies GmbH
R1458C2	Rabbit IgG (H+L chain, adsorbed) antibody
	Goat	Cy2
					OriGene Technologies GmbH
R1458C3	Rabbit IgG (H+L chain, adsorbed) antibody
	Goat	Cy3
					OriGene Technologies GmbH
R1458C5	Rabbit IgG (H+L chain, adsorbed) antibody
	Goat	Cy5
					OriGene Technologies GmbH

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DP3506S FGF basic / FGF2 antibody

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Product Description for FGF basic / FGF2

Properties for FGF basic / FGF2

Datasheet Extract

Accessory Products

Proteins and/or Positive Controls

Proteins for FGF basic / FGF2 (31 products)

Recommended Secondary Antibodies for FGF basic / FGF2 (9 products)

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