PTPRE antibody

Principal name

PTPRE antibody

Alternative names for PTPRE antibody

Protein-tyrosine phosphatase epsilon, R-PTP-epsilon, Receptor-type tyrosine-protein phosphatase epsilon

SwissProt ID

B2GV87 (Rat), P23469 (Human), P49446 (Mouse)

Gene ID

5791 (PTPRE), 19267 (Ptpre), 114767

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Mky (Monkey)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F)

Background of PTPRE antibody

PTPRE is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.

General readings

Weiss,B. (2008) J. Biol. Chem. 283 (8), 4612-4621

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CRISPR

Catalog No. Species Donor Vector  

PTPRE - human gene knockout kit via CRISPR

PTPRE - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / $1,290.00
  OriGene Technologies, Inc.

PTPRE - human gene knockout kit via CRISPR

PTPRE - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / $1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTPRE (transcript variant 1)

  Recombinant protein of human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1  
PTPRE Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $748.00
  OriGene Technologies, Inc.

PTPRE (transcript variant 2)

  Recombinant protein of human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 2  
PTPRE Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $748.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PTPRE overexpression lysate

PTPRE overexpression lysate  
0.1 mg / $495.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ptpre (GFP-tagged ORF) - Rat protein tyrosine phosphatase, receptor type, E (Ptpre), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptpre (GFP-tagged ORF) - Rat protein tyrosine phosphatase, receptor type, E (Ptpre), 200 uL, >10^7 TU/mL  
200 µl / $1,460.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ptpre (Myc-DDK-tagged ORF) - Rat protein tyrosine phosphatase, receptor type, E (Ptpre), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptpre (Myc-DDK-tagged ORF) - Rat protein tyrosine phosphatase, receptor type, E (Ptpre), 200 uL, >10^7 TU/mL  
200 µl / $1,320.00
  OriGene Technologies, Inc.

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