STAT3 - AM06296SU-N | acris-antibodies.com

Product Description for STAT3

Mouse anti Human STAT3 7G3H4.
Presentation: Ascites
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Product Category	Primary Antibodies
Target Category	STAT3 antibody
Quantity	0.1 ml
Synonyms	APRF, Acute-phase response factor, STAT-3, Signal transducer and activator of transcription 3
Presentation	Ascites
Reactivity	Hu
Applications	E, P, WB
Clonality	Monoclonal
Clone	7G3H4
Host	Mouse
Isotype	IgG1
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Monoclonal Antibodies (de)

Immunogen	Swiss Prot Num: P40763 Immunogen: Purified recombinant fragment of STAT3 expressed in E. Coli. GeneID: 6774
Application	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Background	STAT3 is a key signaling molecule for many cytokines and growth-factor receptors and is required for murine fetal development. STAT3 is also constitutively activated in a number of human tumors, possesses oncogenic potential, and anti-apoptotic activities. Following phosphorylation at Y705, STAT3 dimerizes, translocates to the nucleus and binds DNA. Transcriptional activation seems to be regulated by phosphorylation at Ser 727. STAT3 exists as an alpha form (86kD) and a beta form (79kD) that lacks a 50 amino acid domain containing Ser 727.
General Readings	APMIS. 2007 Dec;115(12):1331-43. Oncol Rep. 2008 Sep;20(3):597-604.
Storage	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	State: Ascitic fluid containing 0.03% Sodium Azide. Ascites
Species Reactivity	Species reactivity (tested): Human.
Specificity	Specificity: Recognizes Signal Transducer and Activator Of Transcription 3 (STAT3).
Gene ID	6774

Catalog No.	Species	Purity	Source
TP312394	STAT3 (transcript variant 3)
	Human	> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.	HEK293 cells	20 µg / $748.00
				OriGene Technologies, Inc.
TP315836	STAT3 (transcript variant 1)
	Human	> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.	HEK293 cells	20 µg / $748.00
				OriGene Technologies, Inc.

Catalog No.	Host	Pres.	Applications
R1253AP	Mouse IgG (H+L chain) antibody
	Rabbit	AP	C, E, WB
				OriGene Technologies GmbH
R1253B	Mouse IgG (H+L chain) antibody
	Rabbit	Biotin	C, E, WB
				OriGene Technologies GmbH
R1253F	Mouse IgG (H+L chain) antibody
	Rabbit	FITC	E, ICC/IF
				OriGene Technologies GmbH
R1253HRP	Mouse IgG (H+L chain) antibody
	Rabbit	HRP	C, E, WB
				OriGene Technologies GmbH
R1253TR	Mouse IgG (H+L chain) antibody
	Rabbit	Texas Red	ICC/IF
				OriGene Technologies GmbH
R1403R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Rabbit	PE	F
				OriGene Technologies GmbH
R1405R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Goat	PE
				OriGene Technologies GmbH
R1455R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Donkey	PE
				OriGene Technologies GmbH
R1457C2	Mouse IgG (H+L chain), adsorbed antibody
	Goat	Cy2
				OriGene Technologies GmbH
R1457C3	Mouse IgG (H+L chain), adsorbed antibody
	Goat	Cy3
				OriGene Technologies GmbH
R1457C5	Mouse IgG (H+L chain), adsorbed antibody
	Goat	Cy5
				OriGene Technologies GmbH