TA501145 PRKAR2A antibody

anti-PRKAR2A (PKA R2 ) mouse monoclonal antibody, clone OTI4H8 (formerly 4H8)

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0.1 ml / $360.00
Delivery Time: 2-3 working days*
(*) valid for US customers only

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Mouse anti Human PRKAR2A OTI4H8

TA501145

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Product Description for PRKAR2A

Mouse anti Human PRKAR2A OTI4H8.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot, Flow Cytometry.

Properties for PRKAR2A

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms PKA R2, PKA RII, PKR2, PRKAR2, cAMP-dependent protein kinase type II-alpha regulatory subunit, protein kinase A RII-alpha
Presentation Purified
Reactivity Hu
Applications F, ICC/IF, P, WB
Clonality Monoclonal
Clone OTI4H8
Host Mouse
Isotype IgG1
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P13861
Immunogen:
Full length human recombinant protein of human PRKAR2A (NP_004148) produced in HEK293T cell.
GeneID:
5576
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application WB 1:2000
IHC 1:50
IF 1:100
Flow: 1:100
Background cAMP is a sigling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kise, which transduces the sigl through phosphorylation of different target proteins. The ictive kise holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the ictive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kise anchoring proteins and determine the subcellular localization of cAMP-dependent protein kise. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).
Format
Purification:
Purified from mouse ascites fluids by affinity chromatography
Buffer System:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for PRKAR2A (6 products)

Catalog No. Species Pres. Purity   Source  

PRKAR2A

PRKAR2A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $748.00
  OriGene Technologies, Inc.

PRKAR2A

PRKAR2A Human Purified > 95.0% as determined by SDS-PAGE E. coli
  OriGene Technologies GmbH

PRKAR2A

PRKAR2A Human Purified > 95.0% as determined by SDS-PAGE E. coli
  OriGene Technologies GmbH

PRKAR2A

PRKAR2A Human Purified > 95.0% as determined by SDS-PAGE E. coli
  OriGene Technologies GmbH

PRKAR2A (1-404, His-tag)

PRKAR2A Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / $820.00
  OriGene Technologies GmbH

PRKAR2A (1-404, His-tag)

PRKAR2A Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / $320.00
  OriGene Technologies GmbH
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