SP1103F Complement C3c antibody

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1 ml / $400.00
Delivery Time: 3-5 working days*
(*) valid for US customers only

Quick Overview

Sheep anti Human Complement C3c

SP1103F

Product Description for Complement C3c

Sheep anti Human Complement C3c.
Presentation: FITC
Product is tested for Frozen Sections.

Properties for Complement C3c

Product Category Primary Antibodies
Target Category
Quantity 1 ml
Synonyms C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3
Presentation FITC
Reactivity Hu
Applications C
Clonality Polyclonal
Host Sheep
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P01024
Immunogen:
Human C3 purified from serum
GeneID:
718
Application Immunohistochemistry on Frozen Sections: 1/50 - 1/100.
Recommended Positive ControlHuman skin.
Background The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
Concentration 10 mg/ml
General Readings
  1. Kennedy MW, Kuo YM. The surfaces of the parasitic nematodes Trichinella spiralis and Toxocara canis differ in the binding of post-C3 components of human complement by the alternative pathway. Parasite Immunol. 1988 Jul;10(4):459-63. PubMed PMID: 2971916.
  2. Oyeyinka GO, Awogun IA, Akande TM, Awarun JA, Arinola OG, Salimonu LS. The effects of ageing on the immune response to Schistosoma haematobium and hookworm by measuring circulating immune complexes, C3, IgG, IgA and IgM levels in residents of Omi dam area of Kogi State, Nigeria. Afr J Med Med Sci. 2003 Sep;32(3):263-7. PubMed PMID: 15030085.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.
Format
Label:
Fluorescein Isothiocyanate Isomer 1 (FITC)-liquid
FITC
Purification:
Ion exchange chromatography
Buffer System:
PBS, pH 7.2 containing 0.09% Sodium Azide as preservative
State:
Liquid purified IgG fraction
Specificity
Specificity:
This antibody recognises the C3c component of complement, formed as a result of the inactivation of C3b. The reagent may be used for the detection of C3 deposits in tissues following complement activation.
Species:
Human.

Accessory Products

Proteins and/or Positive Controls

Proteins for Complement C3c (5 products)

Catalog No. Species Pres. Purity   Source  

Complement C3

Complement C3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $788.00
  OriGene Technologies, Inc.

Complement C3

Complement C3 Human Purified > 96 % pure by SDS-PAGE
Analysis: Cellulose acetate electrophoresis shows one band only with beta-2 electrophoretic mobility. Quantitative and qualitative analysis by radial immunodiffusion.
Plasma
  OriGene Technologies GmbH

Complement C3

Complement C3 Human > 99 % Serum
  BBI Solutions

Complement C3

Complement C3 Human > 96 % Serum
  BBI Solutions

Complement C3b

Complement C3b Human Purified > 90 % by SDS-PAGE Serum
0.1 mg / $720.00
  OriGene Technologies GmbH
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