Product Description for Complement C3
Complement C3.
Presentation: Purified
Presentation: Purified
Properties for Complement C3
| Product Category | Proteins & Growth Factors |
|---|---|
| Target Category | |
| Quantity | 1 mg |
| Synonyms | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3 |
| Presentation | Purified |
| Source | Plasma |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 96 % pure by SDS-PAGE Analysis: Cellulose acetate electrophoresis shows one band only with beta-2 electrophoretic mobility. Quantitative and qualitative analysis by radial immunodiffusion. |
| Application | ELISA. |
| Background | C3 is a complement protein that is activated through cleavage by complement 3 (C3) convertases to C3a and C3b. These are further degraded into iC3b and C3dg/C3d. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation. |
| General Readings |
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| Storage | Store lyophilised material at 2-8°C and reconstituted at -20°C. Do not subject to freeze-thaw cycles. Shelf life: one year from despatch. |
| Source | (Human) |
| Description |
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| Format |
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