UHRF1BP1 antibody
Principal name
UHRF1BP1 antibody
Alternative names for UHRF1BP1 antibody
UHRF1-binding protein 1, C6orf107, ICBP90-binding protein 1, Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1
SwissProt ID
Gene ID
54887 (UHRF1BP1)
Available reactivities
Available hosts
Available applications
Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Western blot / Immunoblot (WB)
Background of UHRF1BP1 antibody
The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.
General readings
Hopfner R, Mousli M, Jeltsch JM, et al.: ICBP90, a novel human CCAAT binding protein, involved in the regulation of Topoisomerase II α expression. Cancer Res.2000; 60:121-8.
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC221458L2V | Lenti ORF particles, UHRF1BP1 (mGFP-tagged)-Human UHRF1 binding protein 1 (UHRF1BP1), 200 uL, >10^7 TU/mL |
|
 |
200 µl /
$2,680.00
|
|
| OriGene Technologies, Inc. | ||
| RC221458L1V | Lenti ORF particles, UHRF1BP1 (Myc-DDK-tagged)-Human UHRF1 binding protein 1 (UHRF1BP1), 200 uL, >10^7 TU/mL |
|
|
200 µl /
$2,420.00
|
|
| OriGene Technologies, Inc. | ||