TMEM59 antibody

Principal name

TMEM59 antibody

Alternative names for TMEM59 antibody

C1orf8, HSPC001, Transmembrane protein 59, Liver membrane-bound protein

SwissProt ID

Q2F7Z7 (Pig), Q3T0Q2 (Bovin), Q9BXS4 (Human), Q9QY73 (Mouse)

Gene ID

9528 (TMEM59), 56374 (Tmem59)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of TMEM59 antibody

Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMEM59 antibody

  Rabbit Polyclonal antibody to TMEM59 (transmembrane protein 59)  
Sample (50 ug of whole cell lysate). A: mouse liver. 10% SDS PAGE. TA308979 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / $415.00
  OriGene Technologies, Inc.

TMEM59 (N-term) antibody

  Rabbit Polyclonal TMEM59 Antibody  
Western blot analysis of TMEM59 in human kidney tissue lysate with TMEM59 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / $415.00
  OriGene Technologies, Inc.

2 Item(s)

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