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TFR2 antibody

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Principal name

TFR2 antibody

Alternative names for TFR2 antibody

Transferrin receptor protein 2

SwissProt ID

B2GUY2 (Rat), Q9JKX3 (Mouse), Q9UP52 (Human)

Gene ID

7036 (TFR2), 50765 (Tfr2), 288562

Ncbi ID

NP_001193784, NP_056614.3, NP_001193784.1, NM_003227, NP_003218, NM_015799, NM_001105916

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TFR2 antibody

This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. 
Function: Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. 
Cellular Location: Cell membrane; Single-pass type II membrane protein. 
Tissue Location: Predominantly expressed in liver. While the alpha form is also expressed in spleen, lung, muscle, prostate and peripheral blood mononuclear cells, the beta form is expressed in all tissues tested, albeit weakly.

AP54229PU-N - TFR2
Western blot analysis using TFR2 Antibody (C-term) Cat.-No AP54229PU-N in NCI-H292, K562 cell line lysates (35ug/lane). This demonstrates the TFR2 antibody detected the TFR2 protein (arrow).
TA504563 - TFR2
Anti-TFR2 mouse monoclonal antibody (TA504563) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TFR2(RC220060).
TA504563 - TFR2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TFR2 (RC220060, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TFR2.
TA504563 - TFR2
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-TFR2 monoclonal antibody.
TA504563 - TFR2
HEK293T cells transfected with either RC220060 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-TFR2 antibody(TA504563), and then analyzed by flow cytometry.
TA504590 - TFR2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TFR2 (RC220060, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TFR2.
TA504592 - TFR2
Anti-TFR2 mouse monoclonal antibody (TA504592) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TFR2(RC220060).
TA504592 - TFR2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TFR2 (RC220060, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TFR2.
TA504592 - TFR2
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-TFR2 monoclonal antibody.
TA504592 - TFR2
HEK293T cells transfected with either RC220060 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-TFR2 antibody(TA504592), and then analyzed by flow cytometry.
TP320060 - TFR2
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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TFR2 antibody
  TFR2 (Transferrin Receptor 2) mouse monoclonal antibody, clone OTI2B4 (formerly 2B4)  
Anti-TFR2 mouse monoclonal antibody (TA504563) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TFR2(RC220060). Mouse IgG2a OTI2B4 Purified Hu, Mky, Ms, Rt F, ICC/IF, WB
0.1 ml / $379.00
  OriGene Technologies, Inc.
+3 additional images

Highly validated antibody!

TrueMAB

TFR2 antibody
  TFR2 (Transferrin Receptor 2) mouse monoclonal antibody, clone OTI1B1 (formerly 1B1)  
Anti-TFR2 mouse monoclonal antibody (TA504592) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TFR2(RC220060). Mouse IgG2a OTI1B1 Purified Hu, Mky, Ms F, ICC/IF, WB
0.1 ml / $360.00
  OriGene Technologies, Inc.
+3 additional images

Highly validated antibody!

TrueMAB

2 Item(s)

per page

Active Filters

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Product Type
  1. Primary Antibody (2)
Clonality
  1. Monoclonal (2)
Target
  1. TFR2 (2)
Reactivity
  1. Human (Hu) (2)
  2. Monkey (Mky) (2)
  3. Mouse (Ms) (2)
  4. Rat (Rt) (1)
Presentation
  1. Purified (2)
Host
  1. Mouse (2)
Images
  1. 1 image (2)
  2. 3+ images (2)
Images: Applications
  1. Flow cytometry (F) (2)
  2. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  3. Western blot / Immunoblot (WB) (2)
Manufacturer
  1. OriGene Technologies (2)
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