SENP2 antibody
Principal name
SENP2 antibody
Alternative names for SENP2 antibody
Sentrin-specific protease 2, Smt3ip2, Axam2, KIAA1331, Sentrin/SUMO-specific protease SENP2, SMT3-specific isopeptidase 2
Ncbi ID
NP_067640, 9606, NP_067640.2, NP_083733.1, NM_029457, NM_023989, NM_021627
Available reactivities
Available hosts
Available applications
Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of SENP2 antibody
SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the “GG” region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates. HIPK2 is a desumoylation target for SENP1 which shuttles between the cytoplasm and the nucleus. Mutation analyses reveal that SENP1 contains the nuclear export sequence (NES) within the extreme carboxyl-terminal region, and SENP1 is exported to the cytoplasm in a NES-dependent manner. SENP2 has been implicated as a downregulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway. SUMO protease SENP3 reverses the sumoylation of MEF-2 to augment its transcriptional and myogenic activities. SENP5 localizes to the nucleolus and preferentially processes SUMO-3. It is thought to play a role in mitosis and/or cytokinesis.































































































































- Quick-Filters:
- Highly Validated (1)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA336351 | SENP2 antibody |
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| Rabbit Polyclonal SENP2 Antibody | |||||||
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Rabbit | Purified | Hu, Ms | P, WB |
0.1 mg /
$335.00
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| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
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| TA308765 | SENP2 antibody |
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| Rabbit Polyclonal antibody to SENP2 (SUMO1/sentrin/SMT3 specific peptidase 2) | |||||||
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Rabbit | IgG | Aff - Purified | Hu | ICC/IF, P, WB |
0.1 ml /
$415.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA315697 | SENP2 antibody |
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| Rabbit polyclonal anti-SENP2 antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, WB |
0.1 ml /
$335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA350401 | SENP2 antibody |
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| Rabbit Polyclonal Anti-SENP2 Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
$335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| AP06457PU-N | SENP2 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | P, WB |
0.1 mg /
$370.00
|
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| OriGene Technologies GmbH | |||||||
| AP11235PU-N | SENP2 (C-term) antibody |
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Rabbit | Ig | Purified | Hu, Ms | P, WB |
0.4 ml /
$415.00
|
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| OriGene Technologies GmbH | |||||||
+1 additional image |
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| AP11236PU-N | SENP2 (C-term) antibody |
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![]() |
Rabbit | Ig | Purified | Hu | P, WB |
0.4 ml /
$415.00
|
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| OriGene Technologies GmbH | |||||||
+1 additional image |
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![Western Blot: SENP2 Antibody [TA336351] - analysis of SENP2 in human Jurkat (A) and mouse NIH 3T3 (B) cell lysate using SENP3 antibody at 3 ug/ml.](https://m1.acris-antibodies.com/catalog/product/cache/2/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NB100-56406-1-W.jpg)
+3 additional images




