SEC63 antibody
Principal name
SEC63 antibody
Alternative names for SEC63 antibody
SEC63L, Translocation protein SEC63 homolog
Ncbi ID
9606, NP_009145, NP_009145.1, NM_007214, NP_694695.3, NM_153055
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))
Background of SEC63 antibody
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. SEC63 is an integral membrane protein located in the rough ER.The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
General readings
Otsuki,T., (2005) DNA Res. 12 (2), 117-126
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP308436 | SEC63 |
||||
| Recombinant protein of human SEC63 homolog (S. cerevisiae) (SEC63) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
$748.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY402111 | SEC63 overexpression lysate |
|
 |
0.1 mg /
$295.00
|
|
| OriGene Technologies, Inc. |
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR210508L2V | Lenti ORF particles, Sec63 (GFP-tagged) - Mouse SEC63-like (S. cerevisiae) (Sec63), 200 uL, >10^7 TU/mL |
|
|
200 µl /
$1,550.00
|
|
| OriGene Technologies, Inc. | ||
| MR210508L1V | Lenti ORF particles, Sec63 (Myc-DDK-tagged) - Mouse SEC63-like (S. cerevisiae) (Sec63), 200 uL, >10^7 TU/mL |
|
|
200 µl /
$1,390.00
|
|
| OriGene Technologies, Inc. | ||