ROR1 antibody

Principal name

ROR1 antibody

Alternative names for ROR1 antibody

NTRKR1, Tyrosine-protein kinase transmembrane receptor ROR1

SwissProt ID

Q01973 (Human), Q24488 (Drome), Q9Z139 (Mouse)

Gene ID

4919 (ROR1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of ROR1 antibody

ROR1, a type I membrane protein, is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, extracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, Xenopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased expression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ROR1 antibody

  ROR1 mouse monoclonal antibody, clone OTI3D11 (formerly 3D11)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ROR1 (RC214967, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ROR1. Mouse IgG1 OTI3D11 Purified Hu WB
0.1 ml / $360.00
  OriGene Technologies, Inc.

TrueMAB

ROR1 antibody

Confocal Immunofluorescence analysis of HEK293 cells trasfected with extracellular ROR1 (aa30-406)-hIgGFc using ROR1 antibody Cat.-No AM06399SU-N (green). Blue: DRAQ5 fluorescent DNA dye. Mouse IgG1 2H6 Ascites Hu E, ICC/IF, WB
0.1 ml / $380.00
  OriGene Technologies GmbH

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