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RGS18 antibody

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Principal name

RGS18 antibody

Alternative names for RGS18 antibody

RGS13, Regulator of G-protein signaling 18

SwissProt ID

Q4L0E8 (Rat), Q99PG4 (Mouse), Q9NS28 (Human)

Gene ID

64407 (RGS18), 64214 (Rgs18)

Ncbi ID

9606, NP_570138, NP_570138.1, NP_075019.1, NM_130782

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of RGS18 antibody

RGS18 is a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

General readings

1. Park IK, Klug CA, Li K, Jerabek L, Li L, Nanamori M, Neubig RR, Hood L, Weissman IL, Clarke MF.
Molecular cloning and characterization of a novel regulator of G-protein signaling from mouse hematopoietic stem cells.
J Biol Chem. 2001 Jan 12;276(2):915-23. PMID: 11042171

H00064407-B02 - RGS18
Western Blot analysis of RGS18 expression in transfected 293T cell line (H00064407-T02) by RGS18 MaxPab polyclonal antibody.Lane 1: RGS18 transfected lysate(25.85 KDa).Lane 2: Non-transfected lysate.
H00064407-B01 - RGS18
Western Blot analysis of RGS18 expression in transfected 293T cell line (H00064407-T01) by RGS18 MaxPab polyclonal antibody.Lane 1: RGS18 transfected lysate(25.96 KDa).Lane 2: Non-transfected lysate.
PAB0228 - RGS18
Western blot analysis of RGS18 in human lung lysate. Using RGS18 polyclonal antibody ( Cat # PAB0228 ) at a dilution of 2 µg/ml.
ARP42804_T100 - RGS18
Human Thymus; WB Suggested Anti-RGS18 Antibody Titration: 5.0ug/ml. Positive Control: Human Thymus; RGS18 antibody - N-terminal region (ARP42804_T100) in Human Thymus cells using Western Blot
ARP42805_P050 - RGS18
Human HepG2; WB Suggested Anti-RGS18 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: HepG2 cell lysate; RGS18 antibody - middle region (ARP42805_P050) in Human HepG2 cells using Western Blot
ARP42853_P050 - RGS18
Mouse Lung; WB Suggested Anti-Rgs18 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Mouse Lung; Rgs18 antibody - N-terminal region (ARP42853_P050) in Mouse Lung cells using Western Blot
TP760101 - RGS18
TA305725 - RGS18
TA305725 (1ug/ml) staining of Human Peripheral Blood Mononucleocytes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
TA336471 - RGS18
Western Blot: RGS18 Antibody [TA336471] - Analysis of RGS18 in human lung lysate using this antibody at a dilution of 2 ug/ml.
TA336970 - RGS18
Western Blot: RGS18 Antibody [TA336970] - Western blot analysis of RGS18 in 1) transfected 293T cells and 2) untransfected 293T cells using TA336970 at 1:500.
TA329546 - RGS18
WB Suggested Anti-Rgs18 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Mouse Lung
TA329536 - RGS18
WB Suggested Anti-RGS18 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HepG2 cell lysate

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RGS18 (C-term) antibody
  Goat Anti-RGS18 Antibody  
TA305725 (1ug/ml) staining of Human Peripheral Blood Mononucleocytes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu WB
0.1 mg / $360.00
  OriGene Technologies, Inc.

RGS18 antibody
  Rabbit Polyclonal RGS18 Antibody  
Western Blot: RGS18 Antibody [TA336471] - Analysis of RGS18 in human lung lysate using this antibody at a dilution of 2 ug/ml. Rabbit Purified Hu WB
0.1 mg / $395.00
  OriGene Technologies, Inc.

RGS18 antibody
  Rabbit Polyclonal RGS18 Antibody  
Western Blot: RGS18 Antibody [TA336970] - Western blot analysis of RGS18 in 1) transfected 293T cells and 2) untransfected 293T cells using TA336970 at 1:500. Rabbit Purified Hu ICC/IF, WB
0.1 ml / $335.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RGS18 (full length, N-term HIS tag)
  Recombinant protein of human regulator of G-protein signaling 18 (RGS18), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
RGS18 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 E. coli
50 µg / $205.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

RGS18 overexpression lysate
RGS18 overexpression lysate  
0.1 mg / $295.00
  OriGene Technologies, Inc.

5 Item(s)

per page

Available Filters

Product Type
  1. Lysate (1)
  2. Primary Antibody (3)
  3. Protein | Growth Factor (1)
Clonality
  1. Polyclonal (3)
Target
  1. RGS18 (4)
Property
  1. C-term (1)
Reactivity
  1. Human (Hu) (3)
Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Presentation
  1. Purified (2)
  2. Aff - Purified (1)
Host
  1. Rabbit (2)
  2. Goat (1)
Images
  1. 1 image (4)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
Species (Protein)
  1. Human (1)
Source
  1. E. coli (1)
Manufacturer
  1. OriGene Technologies (5)
Service
 
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