PXK antibody
Principal name
PXK antibody
Alternative names for PXK antibody
MONaKA, FLJ20335, PX domain-containing protein kinase-like protein, Modulator of Na,K-ATPase
Ncbi ID
9606, NP_060241, NP_060241.2, NM_178279, NM_182821, NM_145458, NM_017771, NP_663433.2
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))
Background of PXK antibody
The serine-threonine protein kise encoded by the AKT1 gene is catalytically ictive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kise. In the developing nervous system AKT is a critical mediator of growth factor-induced neurol survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kise AKT1, which then phosphorylates and ictivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple altertively spliced transcript variants have been found for this gene.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA346877 | PXK antibody |
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| Mouse Monoclonal AKT1 Antibody | |||||||
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Mouse | IgG2a | 2D9-D2-H3 | Purified | WB |
0.1 ml /
$335.00
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| OriGene Technologies, Inc. | |||||||
 +1 additional image |
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