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PTPRA antibody

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Principal name

PTPRA antibody

Alternative names for PTPRA antibody

PTPA, PTP alpha, R-PTP-alpha, PTPRL2, Protein-tyrosine phosphatase alpha, Receptor-type tyrosine-protein phosphatase alpha

SwissProt ID

P18052 (Mouse), P18433 (Human), Q03348 (Rat)

Gene ID

5786 (PTPRA)

Ncbi ID

9606, NP_002827, NM_080840, NM_080841, NP_543031, NP_002827.1, NM_002836

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Rt (Rat), Ze (Zebrafish), African clawed frog, Mky (Monkey), Rb (Rabbit), Sh (Sheep), Gorilla

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of PTPRA antibody

Phosphorylation of receptors by protein kinases is a process that can be reversed by a group of enzymes called protein phosphatases. Coordinated control of kinases and phosphatases provides the cell with the capacity to rapidly switch between phosphorylated and dephosphorylated protein states in dynamic response to environmental stimuli. Activation of critical enzymes by kinase phosphorylation alone is not enough to provide adequate regulation ? it is the combination with phosphatase dephosphorylation that effectively creates on/off switches to control cellular events. Errors in control, either through kinases or their counterpart phosphatases, can lead to unchecked cell growth attributable to human cancers and developmental disorders. Potential mechanisms to control dephosphorylation include changes in the expression of protein phosphatases, their subcellular localization, phosphorylation of phosphatase catalytic and regulatory subunits and regulation by endogenous phosphatase inhibitors. Most protein phosphatases are not stringently specific for their substrates. Consequently, changes in phosphatase activity may have a broad impact on dephosphorylation and turnover of phosphoproteins that are substrates for different kinases. This may be an important point of control to connect cellular circuitry of interrelated signaling pathways, and to synchronize physiological responses.

PAB4090 - PTPRA
The PTPRA polyclonal antibody ( Cat # PAB4090 ) is used in Western blot to detect PTPRA in mouse brain tissue lysate.
AP15220PU-N - PTPRA
The anti-PTPalpha N-term Pab is used in Western blot to detect PTPalpha in mouse brain tissue lysate.
ARP45366_P050 - PTPRA
Human 293T; WB Suggested Anti-PTPRA Antibody Titration: 0.2-1 ug/ml. Positive Control: 293T cell lysate. PTPRA is supported by BioGPS gene expression data to be expressed in HEK293T.; PTPRA antibody - C-terminal region (ARP45366_P050) in Human 293T cells using Western Blot
A0562-1 - PTPRA
Western blot analysis of extracts from HeLa cells treated with serum 20% 15', using PTPRA (Phospho-Tyr798) Antibody. The lane on the right is treated with the synthesized peptide.
TP304392 - PTPRA
TP322592 - PTPRA
CPA4500-100ul - PTPRA
Western blot analysis of PTP alpha (pY798) expression in HT29 (A); NIH3T3 (B) whole cell lysates.
TA317220 - PTPRA
Anti-PTPRA antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
TA317220 - PTPRA
Anti-PTPRA antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
TA317221 - PTPRA
Anti-PTPRA antibody IHC of human breast, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 4 ug/ml.
TA317221 - PTPRA
Anti-PTPRA antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 4 ug/ml.
TA317222 - PTPRA
Anti-PTPRA antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
TA317222 - PTPRA
Anti-PTPRA antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
TA317222 - PTPRA
Anti-PTPRA / RPTP-Alpha antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTPRA (Cytopl. Dom.) antibody
  PTPRA Rabbit Polyclonal (Cytoplasmic Domain) Antibody  
PTPRA Rabbit Aff - Purified Hu P
50 µg / $425.00
  OriGene Technologies, Inc.

PTPRA (Cytoplasm. Dom.) antibody
  PTPRA Rabbit Polyclonal (Cytoplasmic Domain) Antibody  
PTPRA Rabbit Aff - Purified Hu P
50 µg / $425.00
  OriGene Technologies, Inc.

PTPRA antibody
  PTPRA Rabbit Polyclonal (Extracellular Domain) Antibody  
Anti-PTPRA antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml. Rabbit IgG Purified Gorilla, Hu, Mky, Rt
50 µg / $425.00
  OriGene Technologies, Inc.
+2 additional images

PTPRA (N-term) antibody
The anti-PTPalpha N-term Pab is used in Western blot to detect PTPalpha in mouse brain tissue lysate. Rabbit Ig Purified Hu, Ms WB
0.4 ml / $415.00
  OriGene Technologies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTPRA (transcript variant 3)
  Recombinant protein of human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 3  
PTPRA Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / $748.00
  OriGene Technologies, Inc.

PTPRA (transcript variant 1)
  Recombinant protein of human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 1  
PTPRA Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / $748.00
  OriGene Technologies, Inc.
 

Lysates

Catalog No.    

PTPRA overexpression lysate
PTPRA overexpression lysate  
0.1 mg / $295.00
  OriGene Technologies, Inc.

PTPRA overexpression lysate
PTPRA overexpression lysate  
0.1 mg / $295.00
  OriGene Technologies, Inc.

PTPRA overexpression lysate
PTPRA overexpression lysate  
0.1 mg / $495.00
  OriGene Technologies, Inc.

9 Item(s)

per page

Available Filters

Product Type
  1. Lysate (3)
  2. Primary Antibody (4)
  3. Protein | Growth Factor (2)
Clonality
  1. Polyclonal (4)
Target
  1. PTPRA (6)
Property
  1. Cytopl. Dom. (1)
  2. Cytoplasm. Dom. (1)
  3. N-term (1)
Reactivity
  1. Human (Hu) (4)
  2. Gorilla (1)
  3. Monkey (Mky) (1)
  4. Mouse (Ms) (1)
  5. Rat (Rt) (1)
Applications
  1. Paraffin Sections (P) (2)
  2. Western blot / Immunoblot (WB) (1)
Presentation
  1. Aff - Purified (2)
  2. Purified (2)
Host
  1. Rabbit (4)
Images
  1. 1 image (4)
  2. 3+ images (1)
Images: Applications
  1. IHC (1)
  2. Western blot / Immunoblot (WB) (1)
Species (Protein)
  1. Human (2)
Source
  1. HEK293 cells (2)
Manufacturer
  1. OriGene Technologies (9)
Service
 
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