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Myosin-Va antibody

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Principal name

Myosin-Va antibody

Alternative names for Myosin-Va antibody

MYO5A, MYH12, Dilute myosin heavy chain, non-muscle, Myosin heavy chain 12, Myoxin

SwissProt ID

Q02440 (Chick), Q99104 (Mouse), Q9QYF3 (Rat), Q9Y4I1 (Human)

Gene ID

4644 (MYO5A), 17918 (Myo5a)

Ncbi ID

9606, NP_000250, NP_000250.3, NP_034994.2

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of Myosin-Va antibody

Myosin-Va has been implicated in the regulation of vesicle trafficking in neurons and melanocytes. It has been suggested that class V myosins associate with membrane vesicles through their C-terminal tails. Myosin V associates with synaptic vesicles and forms a stable complex with the synaptic vesicle membrane proteins, synaptobrevin II, and synaptophysin. The dilute Myo5a gene mutation in myosin Va leads to mental retardation, variable cellular immunodeficiency and impaired melanocyte function (pigmentary dilution), known as Griscelli syndrome in humans. Myosin Va regulates melanosome distribution along microfilaments. It is found in association with the centrosome at all stages of the cell cycle. In the interphase stage, myosin Va is found in pericentriolar material. During cell division, it is found in the cytoplasm and concentrates in a trail between migrating centrioles and in the mitotic spindle poles and spindle fibers.

TA311121 - Myosin-Va
(1ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
TA311121 - Myosin-Va
(1ug/ml) staining of Mouse Skeletal Muscle (first panel, and in green in third panel). Alpha-bungaratoxin staining in middle panel and in red in third panel. Detected by Fluorescence. Data kindly provided by Dr. R?diger Rudolf, Karlsruhe, Germany
TA314229 - Myosin-Va
Western blot analysis of extracts from HeLa cells, using MYO5A antibody.The lane on the right is treated with the synthesized peptide.

2 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Myosin-Va antibody
  Goat Anti-MYO5A Antibody  
(1ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / $360.00
  OriGene Technologies, Inc.
+1 additional image

Myosin-Va antibody
  Rabbit polyclonal anti-MYO5A antibody  
Western blot analysis of extracts from HeLa cells, using MYO5A antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / $335.00
  OriGene Technologies, Inc.

2 Item(s)

per page

Available Filters

Product Type
  1. Primary Antibody (2)
Clonality
  1. Polyclonal (2)
Target
  1. Myosin-Va (2)
Reactivity
  1. Human (Hu) (2)
  2. Mouse (Ms) (2)
  3. Bovine (Bov) (1)
  4. Rat (Rt) (1)
Applications
  1. Enzyme Immunoassay (E) (2)
  2. Western blot / Immunoblot (WB) (2)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Presentation
  1. Aff - Purified (1)
  2. Purified (1)
Host
  1. Goat (1)
  2. Rabbit (1)
Images
  1. 1 image (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Immunofluorescence (IF) (1)
Manufacturer
  1. OriGene Technologies (2)
Service
 
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