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MIA antibody

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Principal name

MIA antibody

Alternative names for MIA antibody

Melanoma inhibitory activity, Melanoma-derived growth regulatory protein

SwissProt ID

Q16674 (Human), Q28038 (Bovin), Q61865 (Mouse), Q62946 (Rat)

Gene ID

8190 (MIA), 12587 (Mia1), 81510 (Mia)

Ncbi ID

9606, NP_001189482.1, NP_006524.1, NP_006524, NP_062267.2, NM_019394, NM_030852, NM_006533

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of MIA antibody

Melanoma Inhibitory Activity (MIA) was originally identified as an inhibitor of the in vitro growth of malignant melanoma cells. It was the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family; Melanoma Inhibitory Activity, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. Melanoma Inhibitory Activity is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of Melanoma Inhibitory Activity may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis.

General readings

Blesch A, Bosserhoff AK, et al. (1994) Cancer Res 54 (21): 5695–701.

C16607-1 - MIA
Immunohistochemistry analysis of paraffin-embedded human heart tissue, using MIA Antibody. The picture on the right is treated with the synthesized peptide.
AP32142PU-N - MIA
Staining of Human Glioma lysate using MIA antibody Cat.-No AP32142PU-N at 1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
AR51317PU-N - MIA
CEK1267 - Human MIA1 ELISA Kit
Representative Standard Curve
TP303245 - MIA
TP720129 - MIA
TP723296 - MIA
TA314721 - MIA
Immunohistochemistry analysis of paraffin-embedded human heart tissue using MIA antibody.The picture on the right is treated with the synthesized peptide.
TA328382 - MIA
IHC of human pancreas infiltrating ductal adenocarcinoma tissue. The recommended concentration is 1.0 ug/ml - 2.0 ug/ml with an overnight incubation at 4C. An HRP-labeled polymer detection system was used with an alcohol-soluble AEC chromogen. Optimal results for these conditions were achieved with heat induced antigen retrieval with a pH 6.0 Sodium Citrate buffer or enzyme induced antigen retrieval with proteinase K at room temperature. Optimal concentrations and conditions may vary.

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MIA antibody
Staining of Human Glioma lysate using MIA antibody Cat.-No AP32142PU-N at 1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / $380.00
  OriGene Technologies GmbH
 

OriGene recommends this product for Western blotting.

MIA antibody
  Rabbit polyclonal anti-MIA antibody  
Immunohistochemistry analysis of paraffin-embedded human heart tissue using MIA antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / $335.00
  OriGene Technologies, Inc.

MIA antibody
  Anti-Human MIA Rabbit Polyclonal Antibody  
IHC of human pancreas infiltrating ductal adenocarcinoma tissue. The recommended concentration is 1.0 ug/ml - 2.0 ug/ml with an overnight incubation at 4C. An HRP-labeled polymer detection system was used with an alcohol-soluble AEC chromogen. Optimal results for these conditions were achieved with heat induced antigen retrieval with a pH 6.0 Sodium Citrate buffer or enzyme induced antigen retrieval with proteinase K at room temperature. Optimal concentrations and conditions may vary. Rabbit IgG Purified Hu E, P, WB
0.1 mg / $275.00
  OriGene Technologies, Inc.

MIA antibody
MIA Rabbit Biotin Hu E, WB
50 µg / $340.00
  OriGene Technologies GmbH

MIA antibody
MIA Rabbit Biotin Hu E, WB
25 µg / $250.00
  OriGene Technologies GmbH

5 Item(s)

per page

Active Filters

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Available Filters

Product Type
  1. Primary Antibody (5)
Target
  1. MIA (5)
Reactivity
  1. Human (Hu) (5)
  2. Mouse (Ms) (1)
Applications
  1. Enzyme Immunoassay (E) (4)
  2. Western blot / Immunoblot (WB) (4)
  3. Paraffin Sections (P) (2)
Presentation
  1. Biotin (2)
  2. Purified (2)
  3. Aff - Purified (1)
Host
  1. Rabbit (4)
  2. Goat (1)
Images
  1. 1 image (3)
Images: Applications
  1. IHC (2)
  2. Western blot / Immunoblot (WB) (1)
Manufacturer
  1. OriGene Technologies (5)
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