MAN1B1 antibody
Principal name
MAN1B1 antibody
Alternative names for MAN1B1 antibody
ER alpha-1,2-mannosidase, Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, Mannosidase alpha class 1B member 1, Man9GlcNAc2-specific-processing alpha-mannosidase
SwissProt ID
Q9UKM7 (Human)
Gene ID
11253 (MAN1B1)
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)
Background of MAN1B1 antibody
ERManI, also known as endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase or MAN1B1, is a putative ER resident mannosidase that plays a rate-limiting role in generating a sigl that targets misfolded N-linked glycoproteins for ER-associated degradation (ERAD). ERManI codes for an enzyme that converts Man9Glcc to Man8Glcc isomer B during N-glycan biosynthesis. It also facilitates the trimming of Man5-6Glcc2 in the endoplasmic reticulum associated degradation pathway. Multiple transcript variants of ERManI can result from altertive splicing, and a related pseudogene can be found on chromosome 11. Research has found that mutations on the ERManI gene can result in autosomal-recessive intellectual disabilities and developmental delays (PMID: 21763484). ERManI is predomitely localized to the Golgi and endoplasmic reticulum.










Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA307927 | MAN1B1 antibody |
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| Rabbit polyclonal antibody to MAN1B1 (mannosidase, alpha, class 1B, member 1) | |||||||
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Rabbit | IgG | Aff - Purified | Hu | P, WB |
0.1 ml /
$415.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA312707 | MAN1B1 antibody |
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| Rabbit polyclonal anti-MAN1B1 antibody | |||||||
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Rabbit | IgG | Purified | Hu | E, WB |
0.1 ml /
$335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA347576 | MAN1B1 antibody |
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| Rabbit Polyclonal Anti-MAN1B1 Antibody | |||||||
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Rabbit | IgG | Purified | Hu | WB |
0.1 mg /
$335.00
|
|
| OriGene Technologies, Inc. | |||||||



+1 additional image
