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MAN1B1 antibody

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Principal name

MAN1B1 antibody

Alternative names for MAN1B1 antibody

ER alpha-1,2-mannosidase, Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, Mannosidase alpha class 1B member 1, Man9GlcNAc2-specific-processing alpha-mannosidase

SwissProt ID

Q9UKM7 (Human)

Gene ID

11253 (MAN1B1)

Ncbi ID

9606, NM_016219, NP_057303, NP_057303.2

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of MAN1B1 antibody

ERManI, also known as endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase or MAN1B1, is a putative ER resident mannosidase that plays a rate-limiting role in generating a sigl that targets misfolded N-linked glycoproteins for ER-associated degradation (ERAD). ERManI codes for an enzyme that converts Man9Glcc to Man8Glcc isomer B during N-glycan biosynthesis. It also facilitates the trimming of Man5-6Glcc2 in the endoplasmic reticulum associated degradation pathway. Multiple transcript variants of ERManI can result from altertive splicing, and a related pseudogene can be found on chromosome 11. Research has found that mutations on the ERManI gene can result in autosomal-recessive intellectual disabilities and developmental delays (PMID: 21763484). ERManI is predomitely localized to the Golgi and endoplasmic reticulum.

H00011253-M01 - MAN1B1
Immunoperoxidase of monoclonal antibody to MAN1B1 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml]
H00011253-M01 - MAN1B1
MAN1B1 monoclonal antibody (M01), clone 6B1. Western Blot analysis of MAN1B1 expression in HepG2 ( Cat # L019V1 ).
H00011253-M01 - MAN1B1
MAN1B1 monoclonal antibody (M01), clone 6B1 Western Blot analysis of MAN1B1 expression in A-431 ( Cat # L015V1 ).
H00011253-M01 - MAN1B1
MAN1B1 monoclonal antibody (M01), clone 6B1. Western Blot analysis of MAN1B1 expression in LNCaP ( Cat # L004V1 ).
H00011253-M01 - MAN1B1
Detection limit for recombinant GST tagged MAN1B1 is approximately 0.03ng/ml as a capture antibody.
TA307927 - MAN1B1
Sample (30 ug of whole cell lysate). A: Hela. 7.5% SDS PAGE. MAN1B1 antibody. TA307927 diluted at 1:1000.
TA307927 - MAN1B1
Immunohistochemical analysis of paraffin-embedded SCC25 xenograft, using MAN1B1(TA307927) antibody at 1:100 dilution.
TA312707 - MAN1B1
Western blot analysis of extracts from 3T3 cells, using MAN1B1 antibody.The lane on the right is treated with the synthesized peptide.
TA336898 - MAN1B1
Western Blot: ERManI Antibody (3C2) [TA336898] - Western blot analysis of ERManI expression in 1) NTERA-2 and 2) A-431 whole cell lysates.
TA336898 - MAN1B1
Immunohistochemistry: ERManI Antibody (3C2) [TA336898] - IHC staining of ERManI in human breast cancer using DAB with hematoxylin counterstain.
TA336898 - MAN1B1
Immunocytochemistry/Immunofluorescence: ERManI Antibody (3C2) [TA336898] - ERManI antibody was tested in HeLa cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).
TA347576 - MAN1B1
Western blot analysis on 3T3 cell lysate using MAN1B1 Antibody

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MAN1B1 antibody
  Mouse Monoclonal ERManI Antibody (3C2)  
Western Blot: ERManI Antibody (3C2) [TA336898] - Western blot analysis of ERManI expression in 1) NTERA-2 and 2) A-431 whole cell lysates. Mouse IgG1 3C2 Purified Hu, Ms C, E, ICC/IF, IP, P, WB
0.1 ml / $395.00
  OriGene Technologies, Inc.
+2 additional images

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Product Type
  1. Primary Antibody (1)
Clonality
  1. Monoclonal (1)
Target
  1. MAN1B1 (1)
Reactivity
  1. Human (Hu) (1)
  2. Mouse (Ms) (1)
Presentation
  1. Purified (1)
Host
  1. Mouse (1)
Images
  1. 1 image (1)
  2. 3+ images (1)
Images: Applications
  1. Immunofluorescence (IF) (1)
  2. IHC (1)
  3. Western blot / Immunoblot (WB) (1)
Manufacturer
  1. OriGene Technologies (1)
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