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KCNV2 antibody

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Principal name

KCNV2 antibody

Alternative names for KCNV2 antibody

KV11.1, Kv8.2, Potassium voltage-gated channel subfamily V member 2

SwissProt ID

Q8CFS6 (Mouse), Q8TDN2 (Human)

Gene ID

169522 (KCNV2), 240595 (Kcnv2)

Ncbi ID

NP_598004, NP_598004.1, NP_899002.1, NM_183179, NM_133497

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of KCNV2 antibody

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a \'silent subunit\', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. KCNV2 is strongly expressed in pancreas and has a weaker expression in several other tissues.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a \'silent subunit\', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.

General readings

Robson, A.G., et al. Retina (Philadelphia, Pa.) 30(1):51-62(2010)
Ben Salah, S., et al. Am. J. Ophthalmol. 145(6):1099-1106(2008)
Wissinger, B., et al. Invest. Ophthalmol. Vis. Sci. 49(2):751-757(2008)
Thiagalingam, S., et al. Ophthalmic Genet. 28(3):135-142(2007)
Balijepalli, R.C., et al. Channels (Austin) 1(4):263-272(2007)

ARP35396_P050 - KCNV2
Human 293T; WB Suggested Anti-KCNV2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: 293T cell lysate; KCNV2 antibody - N-terminal region (ARP35396_P050) in Human 293T cells using Western Blot
C17829-1 - KCNV2
Western blot analysis of extracts from MCF-7 cells, using KCNV2 Antibody. The lane on the right is treated with the synthesized peptide.
AP52321PU-N - KCNV2
Immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue reacted with KCNV2 Antibody (C-term) Cat.-No AP52321PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining.
AP52321PU-N - KCNV2
Western blot analysis of KCNV2 Antibody (C-term) Cat.-No AP52321PU-N in 293, K562, HepG2, Jurkat, ZR-75-1 cell line lysates (35ug/lane). This demonstrates the KCNV2 antibody detected the KCNV2 protein (arrow).
TA316201 - KCNV2
Western blot analysis of extracts from Jurkat cells, using OR4K3 antibody.The lane on the right is treated with the synthesized peptide.
TA316201 - KCNV2
Immunofluorescence analysis of A549 cells, using OR4K3 antibody.The picture on the right is treated with the synthesized peptide.
TA338726 - KCNV2
WB Suggested Anti-KCNV2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: 293T cell lysate
CPA9413-100ul - KCNV2
Western blot analysis of Kv8.2 expression in mouse brain (A); rat brain (B) whole cell lysates.
CPA9413-100ul - KCNV2
Immunohistochemical analysis of Kv8.2 staining in mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNV2 antibody
  Rabbit polyclonal anti-OR4K3 antibody  
Western blot analysis of extracts from Jurkat cells, using OR4K3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, WB
0.1 ml / $335.00
  OriGene Technologies, Inc.
+1 additional image

KCNV2 (C-term) antibody
Immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue reacted with KCNV2 Antibody (C-term) Cat.-No AP52321PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / $415.00
  OriGene Technologies GmbH
+1 additional image

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kcnv2 (GFP-tagged) - Mouse potassium channel, subfamily V, member 2 (Kcnv2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Kcnv2 (GFP-tagged) - Mouse potassium channel, subfamily V, member 2 (Kcnv2), 200 uL, >10^7 TU/mL  
200 µl / $1,280.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Kcnv2 (Myc-DDK-tagged) - Mouse potassium channel, subfamily V, member 2 (Kcnv2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Kcnv2 (Myc-DDK-tagged) - Mouse potassium channel, subfamily V, member 2 (Kcnv2), 200 uL, >10^7 TU/mL  
200 µl / $1,150.00
  OriGene Technologies, Inc.
 

4 Item(s)

per page

Available Filters

Product Type
  1. Mouse Lenti ORF Particle (2)
  2. Primary Antibody (2)
Clonality
  1. Polyclonal (2)
Target
  1. KCNV2 (2)
Property
  1. C-term (1)
Reactivity
  1. Human (Hu) (2)
Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Enzyme Immunoassay (E) (1)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
  4. Paraffin Sections (P) (1)
Presentation
  1. Aff - Purified (1)
  2. Purified (1)
Host
  1. Rabbit (2)
Images
  1. 1 image (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Immunofluorescence (IF) (1)
  3. Paraffin Sections (P) (1)
Manufacturer
  1. OriGene Technologies (4)
Service
 
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