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Galectin-4 antibody

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Principal name

Galectin-4 antibody

Alternative names for Galectin-4 antibody

LGALS4, Galectin4, Lactose-binding lectin 4, L-36 lactose-binding protein, L36LBP, Antigen NY-CO-27

SwissProt ID

P07583 (Chick), P38552 (Rat), P56470 (Human), Q29058 (Pig), Q3T0D6 (Bovin), Q8K419 (Mouse)

Gene ID

3960 (LGALS4), 16855 (Lgals4), 25474

Ncbi ID

9606, NP_006140, NP_006140.1, NM_010706, NP_034836.1, NM_012975, NM_006149

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of Galectin-4 antibody

Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One member of this family, Galectin-4, also known as Gal-4, L36 or LGALS4 maps to human chromosome 19q13.13 and encodes a 36-37 kDa protein. The Galectin-4 protein is composed of 323 amino acids and contains two homologous carbohydrate recognition domains (CRD) and all amino acids typically conserved in the galectin family. Expression of Galectin-4 correlates with the malignant potential of human hepatocellular carcinoma (HCC) and is differentially regulated depending on cell-cell contact, serum growth factors, cell growth and cell differentiation status. Galectin-4 expression is detected in epithelial cells of the colon, rectum, intestine, and in HT29 and LS174T cell lines. Galectin-4 is underexpressed in colorectal cancer and is preferentially upregulated in cells prone to peritoneal dissemination.

General readings

Zimbardi, A.L., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (PT 5), 542-545 (2010)
Stechly, L., et al. Traffic 10(4):438-450(2009)
Tripodi, D., et al. BMC Med Genomics 2, 65 (2009)
Oberg, C.T., et al. Bioorg. Med. Chem. Lett. 18(13):3691-3694(2008)
Ideo, H., et al. J. Biol. Chem. 282(29):21081-21089(2007)

AR09292PU-L - Galectin-4
Recombinant human Galectin- 4 (1-323 aa), His-tagged: 15% SDS-PAGE (3 µg)
AP20547PU-N - Galectin-4
Immunohistochemistry (IHC) analyzes of Galectin-4 antibody (Cat.-No.: AP20547PU-N) in paraffin-embedded human liver carcinoma tissue.
AP20547PU-N - Galectin-4
Western blot (WB) analysis of Galectin-4 antibody (Cat.-No.: AP20547PU-N) in extracts from COLO cells.
C13077-1 - Galectin-4
Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using LEG4 Antibody. The picture on the right is treated with the synthesized peptide.
C13077-1 - Galectin-4
Western blot analysis of extracts from COLO cells, using LEG4 Antibody. The lane on the right is treated with the synthesized peptide.
ARP42280_P050 - Galectin-4
Mouse Brain; WB Suggested Anti-Lgals4 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Mouse Brain; Lgals4 antibody - C-terminal region (ARP42280_P050) in Mouse Brain cells using Western Blot
AM31810PU-N - Galectin-4
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
AP52469PU-N - Galectin-4
Flow cytometric analysis of Jurkat cells using Galectin-4 Antibody (N-term) Cat.-No AP52469PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
AP52469PU-N - Galectin-4
Western blot analysis of Galectin-4 Antibody (N-term) Cat.-No AP52469PU-N in Jurkat cell line lysates (35ug/lane). This demonstrates the LGALS4 antibody detected the LGALS4 protein (arrow).
AR50608PU-N - Galectin-4
CEK1170 - Human Galectin 4 ELISA Kit
Representative Standard Curve
TP300026 - Galectin-4
TA314152 - Galectin-4
Western blot analysis of extracts from HeLa cells, using LEG7 antibody.The lane on the right is treated with the synthesized peptide.
TA314152 - Galectin-4
Western blot analysis of extracts from COLO cells, using LEG4 antibody.The picture on the right is treated with the synthesized peptide.
TA346427 - Lgals4
WB Suggested Anti-Lgals4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Mouse Brain

3 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Galectin-4 antibody
  Rabbit polyclonal anti-LEG4 antibody  
Western blot analysis of extracts from HeLa cells, using LEG7 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified
0.1 ml / $335.00
  OriGene Technologies, Inc.
+1 additional image

Galectin-4 antibody
Immunohistochemistry (IHC) analyzes of Galectin-4 antibody (Cat.-No.: AP20547PU-N) in paraffin-embedded human liver carcinoma tissue. Rabbit Aff - Purified Hu P, WB
0.1 mg / $370.00
  OriGene Technologies GmbH
+1 additional image

Galectin-4 (N-term) antibody
Flow cytometric analysis of Jurkat cells using Galectin-4 Antibody (N-term) Cat.-No AP52469PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / $415.00
  OriGene Technologies GmbH
+1 additional image

3 Item(s)

per page

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Product Type
  1. Primary Antibody (3)
Clonality
  1. Polyclonal (3)
Target
  1. Galectin-4 (3)
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Reactivity
  1. Human (Hu) (2)
Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Flow cytometry (F) (1)
  3. Paraffin Sections (P) (1)
Presentation
  1. Aff - Purified (2)
  2. Purified (1)
Images
  1. 1 image (3)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
  2. IHC (1)
  3. Paraffin Sections (P) (1)
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  1. OriGene Technologies (3)
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