Ficolin-1 antibody

Background of Ficolin-1 antibody

The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-termil segment, followed by a collagen-like region, and a C-termil fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tescins. However, all these proteins recognize different targets, and are functiolly distinct. Ficolin 1(FCN1) is predomintly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity.The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-termil segment, followed by a collagen-like region, and a C-termil fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tescins. However, all these proteins recognize different targets, and are functiolly distinct. Ficolin 1 encoded by FCN1 is predomintly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.