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COG2 antibody

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Principal name

COG2 antibody

Alternative names for COG2 antibody

COG complex subunit 2, LDLC, Conserved oligomeric Golgi complex subunit 2, Component of oligomeric Golgi complex 2, Low density lipoprotein receptor defect C-complementing protein

SwissProt ID

Q14746 (Human), Q921L5 (Mouse)

Gene ID

22796 (COG2), 76332 (Cog2)

Ncbi ID

9606, NP_031383, NP_031383.1, NP_084022.2, NM_029746, NM_007357

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Ze (Zebrafish), Bov (Bovine), Eq (Equine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Flow Cytometry (F)

Background of COG2 antibody

Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2. Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2 (Ungar et al., 2002 [PubMed 11980916]).[supplied by OMIM].

General readings

Sohda,M., (2007) Traffic 8 (3), 270-284

H00022796-M09 - COG2
Western blot analysis of COG2 over-expressed 293 cell line, cotransfected with COG2 Validated Chimera RNAi ( Cat # H00022796-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with COG2 monoclonal antibody (M09), clone 4C8 (Cat # H00022796-M09 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
H00022796-M09 - COG2
Western Blot analysis of COG2 expression in transfected 293T cell line by COG2 monoclonal antibody (M09), clone 4C8.Lane 1: COG2 transfected lysate(83.2 KDa).Lane 2: Non-transfected lysate.
H00022796-A01 - COG2
COG2 polyclonal antibody (A01), Lot # 070226JCSa. Western Blot analysis of COG2 expression in Raw 264.7.
H00022796-A01 - COG2
COG2 polyclonal antibody (A01), Lot # 070226JCSa Western Blot analysis of COG2 expression in Hela NE ( Cat # L013V3 ).
H00022796-A01 - COG2
COG2 polyclonal antibody (A01), Lot # 070226JCSa. Western Blot analysis of COG2 expression in PC-12.
H00022796-B01 - COG2
Western Blot analysis of COG2 expression in transfected 293T cell line (H00022796-T01) by COG2 MaxPab polyclonal antibody.Lane 1: COG2 transfected lysate(81.18 KDa).Lane 2: Non-transfected lysate.
H00022796-M01 - COG2
COG2 monoclonal antibody (M01), clone 3H8. Western Blot analysis of COG2 expression in IMR-32 ( Cat # L008V1 ).
H00022796-B01P - COG2
Western Blot analysis of COG2 expression in transfected 293T cell line (H00022796-T01) by COG2 MaxPab polyclonal antibody.Lane 1: COG2 transfected lysate(81.18 KDa).Lane 2: Non-transfected lysate.
H00022796-D01P - COG2
Western Blot analysis of COG2 expression in transfected 293T cell line (H00022796-T02) by COG2 MaxPab polyclonal antibody.Lane 1: COG2 transfected lysate(83.20 KDa).Lane 2: Non-transfected lysate.
ARP54815_P050 - COG2
Human HepG2; WB Suggested Anti-COG2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate. COG2 is supported by BioGPS gene expression data to be expressed in HepG2.; COG2 antibody - N-terminal region (ARP54815_P050) in Human HepG2 cells using Western Blot
AP51004PU-N - COG2
COG2 Antibody (N-term) (AP51004PU-N) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the COG2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
AP51004PU-N - COG2
Western blot analysis of COG2 Antibody (N-term) (Cat. #AP51004PU-N) in Hela cell line lysates (35µg/lane). COG2 (arrow) was detected using the purified Pab.
AP51004PU-N - COG2
COG2 Antibody (N-term) (Cat. #AP51004PU-N) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
TP304855 - COG2
TA334420 - COG2
WB Suggested Anti-COG2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: HepG2 cell lysateCOG2 is supported by BioGPS gene expression data to be expressed in HepG2

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

COG2 (N-term) antibody
COG2 Antibody (N-term) (AP51004PU-N) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the COG2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / $415.00
  OriGene Technologies GmbH
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