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Carboxypeptidase E antibody

Principal name

Carboxypeptidase E antibody

Alternative names for Carboxypeptidase E antibody

CPE, Carboxypeptidase H, Enkephalin convertase, Prohormone-processing carboxypeptidase

SwissProt ID

P04836 (Bovin), P15087 (Rat), P16870 (Human), Q00493 (Mouse)

Gene ID

1363 (CPE), 12876 (Cpe), 25669

Ncbi ID

NP_001864.1, 9606, NP_001864, NM_001873, NP_038522.2, NM_013494, NM_013128

Available reactivities

Mam (Mammalia), Bov (Bovine), Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat), Chk (Chicken), Por (Porcine), Ze (Zebrafish), African clawed frog

Available hosts

Rabbit

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of Carboxypeptidase E antibody

CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteinsThis gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Chu,K.Y., et al. (2011) Islets 3 (4), 155-165Lee,T.K.,et al. (2011) J. Clin. Invest. 121 (3), 880-892

Human Brain; Immunohistochemistry with Brain, cerebellum tissue at an antibody concentration of 5ug/ml using anti-CPE antibody (ARP58445_P050); CPE antibody - N-terminal region (ARP58445_P050) in Human Brain cells using Immunohistochemistry

ARP58445_P050

Human Pineal Tissue; Rabbit Anti-CPE Antibody . Catalog Number: ARP58445_P050 . Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue . Observed Staining: Cytoplasmic in cell bodies and processes of pinealocytes . Primary Antibody Concentration: 1:100 . Other Working Concentrations: 1/600 . Secondary Antibody: Donkey anti-Rabbit-Cy3 . Secondary Antibody Concentration: 1:200 . Magnification: 20X . Exposure Time: 0.5 - 2.0 sec .; Rabbit Anti-CPE Antibody (ARP58445_P050) ) in Human Pineal Tissue using Immunohistochemistry

ARP58445_P050

Human HepG2; Host:Rabbit. Target Name:CPE. Sample Tissue:HepG2. Antibody Dilution: 1.0ug/ml. CPE is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells.; CPE antibody - N-terminal region (ARP58445_P050) in Human HepG2 cells using Western Blot

ARP58445_P050

Hum. Fetal Heart; Host:Rabbit. Target Name:CPE. Sample Tissue:Human Fetal Heart. Antibody Dilution: 1.0ug/ml.; CPE antibody - N-terminal region (ARP58445_P050) in Hum. Fetal Heart cells using Western Blot

ARP58445_P050

Human MCF7; WB Suggested Anti-CPE Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: MCF7 cell lysate. CPE is supported by BioGPS gene expression data to be expressed in MCF7.; CPE antibody - N-terminal region (ARP58445_P050) in Human MCF7 cells using Western Blot

ARP58445_P050

Hum. Fetal Lung; Host:Rabbit. Target Name:CPE. Sample Tissue:Human Fetal Lung. Antibody Dilution: 1.0ug/ml.; CPE antibody - N-terminal region (ARP58445_P050) in Hum. Fetal Lung cells using Western Blot

ARP58445_P050

Western blot analysis of extracts from RAW264.7/NIH-3T3 cells, using CPE Antibody. The lane on the right is treated with the synthesized peptide.

Western blot analysis of Carboxypeptidase E expression in NIH3T3 (A); PC12 (B) whole cell lysates.

TP308791

Western blot analysis of extracts from 3T3 cells and RAW264.7cells, using CPE antibody.The lane on the right is treated with the synthesized peptide.

TA313672

Western blot analysis of extracts of various cell lines, using CPE antibody.

TA332699

Immunofluorescence analysis of U20S cell using CPE antibody. Blue: DAPI for nuclear staining.

TA332699

Host:Rabbit; Target Name:CPE; Sample Tissue:Human Fetal Lung; Antibody Dilution: 1.0 ug/ml

TA344338

Host:Rabbit; Target Name:CPE; Sample Tissue:Human Fetal Heart; Antibody Dilution: 1.0 ug/ml

TA344338

Host:Rabbit; Target Name:CPE; Sample Tissue:HepG2; Antibody Dilution: 1.0 ug/mlCPE is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells

TA344338

WB Suggested Anti-CPE Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: MCF7 cell lysateCPE is supported by BioGPS gene expression data to be expressed in MCF7

TA344338

Immunohistochemistry with Brain, cerebellum tissue at an antibody concentration of 5 ug/ml using anti-CPE antibody

TA344338

Rabbit Anti-CPE Antibody; Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue; Observed Staining: Cytoplasmic in cell bodies and processes of pinealocytes; Primary Antibody Concentration: 1:100; Other Working Concentrations: 1/600; Secondary Anti

TA344338

Primary Antibodies

Catalog No.	Host	Pres.	React.	Applications
SP1379P	Carboxypeptidase E (C-term) antibody
	Rabbit	Serum	Bov, Hu, Mky, Ms, Rt	C, IP, WB	0.1 ml / $590.00
					OriGene Technologies GmbH

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