Home » Target » Cadherin-23 antibody

Cadherin-23 antibody

Principal name

Cadherin-23 antibody

Alternative names for Cadherin-23 antibody

CDH23, KIAA1774, KIAA1812

SwissProt ID

P58365 (Rat), Q99PF4 (Mouse), Q9H251 (Human)

Gene ID

64072 (CDH23)

Ncbi ID

NP_001165401, NP_001165401.1, ADZ15527.1, NM_052836, NP_443068, NM_001171935, NM_001171931, NM_001171934, NM_001171933, NM_001171930

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Cadherin-23 antibody

Cadherin like 23 (or Cadherin 23) is, like other members of the cadherin family, a calcium-dependent cell adhesion glycoprotein that preferentially interacts with itself in connecting cells. It is a single pass type I membrane protein that contains 27 cadherin domains. Cadherin like 23 is expressed in the neurosensory epithelium, where it is thought to be involved in stereocilia organisation and hair bundle formation. Defects in the gene encoding Cadherin like 23 are a cause of Usher syndrome, which is characterised by profound congenital sensorineural deafness and eventual blindness. Mutations in this gene are also a cause of non-syndromic sensorineural deafness autosomal recessive type 12 (DFNB12). Cadherin like 23 has also been associated with age-related hearing loss.

General readings

Roux AF, Faugère V, Le Guédard S, Pallares-Ruiz N, Vielle A, Chambert S, Marlin S, Hamel C, Gilbert B, Malcolm S, Claustres M; French Usher Syndrome Collaboration.
Survey of the frequency of USH1 gene mutations in a cohort of Usher patients shows the importance of cadherin 23 and protocadherin 15 genes and establishes a detection rate of above 90%.
J Med Genet. 2006 Sep;43(9):763-8.
PMID: 16679490

CDH23 polyclonal antibody ( Cat # PAB11508 ) ( 1 µg/ml ) staining of human amygdala lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence.

PAB11508

Human OVCAR-3; WB Suggested Anti-CDH23 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: OVCAR-3 cell lysate; CDH23 antibody - middle region (ARP49690_P050) in Human OVCAR-3 cells using Western Blot

ARP49690_P050

Immunofluorescence analysis of HeLa cells, using CDH23 Antibody. The picture on the right is treated with the synthesized peptide.

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

AP31877PU-N

Immunofluorescence analysis of HeLa cells, using CDH23 Antibody. The picture on the right is treated with the synthesized peptide.

AP31877PU-N

TP315133

TA305883 (1ug/ml) staining of Human Amygdala lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

TA305883

Immunofluorescence analysis of HeLa cells, using CDH23 antibody.The picture on the right is treated with the synthesized peptide.

TA315715

Predicted band size: 45 kDa . Positive control: Mouse brain tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/1050dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 seconds)

TA324066

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human lung cancer tissue. Recommended dilution: 1/100-300 The image on the left is immunohistochemistry of paraffin-embedded human lung cancer tissue using CDH23 antibody at dilution 1/80, on the right is treated with the fusion protein. (Original magnification:x200)

TA324066

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human colon and thyroid cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using CDH23 antibody at dilution 1/60, on the right is treated with the fusion protein. (Original magnification:x 200)

TA324067

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human colon and thyroid cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using CDH23 antibody at dilution 1/60, on the right is treated with the fusion protein. (Original magnification:x200)

TA324067

Western blot analysis of extracts of Mouse brain, using CDH23 antibody.

TA327417

Host: Rabbit; Target Name: CDH23; Sample Tissue: Fetal Brain lysates; Antibody Dilution: 1.0 ug/ml

TA338484

WB Suggested Anti-CDH23 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: OVCAR-3 cell lysate

TA338485

Primary Antibodies

Catalog No.	Host	Iso.	Pres.	React.	Applications
TA305883	Cadherin-23 antibody
	Goat Anti-CDH23 / USH1D Antibody
	Goat		Aff - Purified	Hu	E, WB	0.1 mg / $360.00
						OriGene Technologies, Inc.
TA315715	Cadherin-23 antibody
	Rabbit polyclonal anti-CDH23 antibody
	Rabbit	IgG	Purified	Hu, Ms	E, ICC/IF	0.1 ml / $335.00
						OriGene Technologies, Inc.
TA324066	Cadherin-23 antibody
	Anti-CDH23 Rabbit Polyclonal Antibody
	Rabbit	IgG	Purified	Hu, Ms, Rt	E, P, WB	0.1 ml / $335.00
						OriGene Technologies, Inc.
+1 additional image
TA324067	Cadherin-23 antibody
	Anti-CDH23 Rabbit Polyclonal Antibody
	Rabbit	IgG	Purified	Hu, Ms, Rt	E, P	0.1 ml / $335.00
						OriGene Technologies, Inc.
+1 additional image
TA327417	Cadherin-23 antibody
	CDH23 Rabbit Polyclonal Antibody
	Rabbit	IgG	Purified	Hu, Ms, Rt	WB	0.1 mg / $335.00
						OriGene Technologies, Inc.
AP31877PU-N	Cadherin-23 (61-110) antibody
	Rabbit	IgG	Aff - Purified	Hu, Ms, Rt	E, ICC/IF, P	50 µl / $425.00
						OriGene Technologies GmbH
+1 additional image

Proteins & Growth Factors

Catalog No.	Species	Purity	Source
TP315133	Cadherin-23 (transcript variant 2)
	Recombinant protein of human cadherin-like 23 (CDH23), transcript variant 2
	Human	> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.	HEK293 cells	20 µg / $748.00
				OriGene Technologies, Inc.

Lysates

Catalog No.
LY409447	CDH23 overexpression lysate
		0.1 mg / $495.00
		OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.
RC230709L2V	Lenti ORF particles, CDH23 (mGFP-tagged)-Human cadherin-related 23 (CDH23), transcript variant 3, 200 uL, >10^7 TU/mL
		200 µl / $2,680.00
		OriGene Technologies, Inc.

RC230634L2V	Lenti ORF particles, CDH23 (mGFP-tagged)-Human cadherin-related 23 (CDH23), transcript variant 4, 200 uL, >10^7 TU/mL
		200 µl / $2,270.00
		OriGene Technologies, Inc.

RC230652L2V	Lenti ORF particles, CDH23 (mGFP-tagged)-Human cadherin-related 23 (CDH23), transcript variant 6, 200 uL, >10^7 TU/mL
		200 µl / $2,370.00
		OriGene Technologies, Inc.

RC230644L2V	Lenti ORF particles, CDH23 (mGFP-tagged)-Human cadherin-related 23 (CDH23), transcript variant 7, 200 uL, >10^7 TU/mL
		200 µl / $2,290.00
		OriGene Technologies, Inc.

RC230709L1V	Lenti ORF particles, CDH23 (Myc-DDK-tagged)-Human cadherin-related 23 (CDH23), transcript variant 3, 200 uL, >10^7 TU/mL
		200 µl / $2,420.00
		OriGene Technologies, Inc.

RC230634L1V	Lenti ORF particles, CDH23 (Myc-DDK-tagged)-Human cadherin-related 23 (CDH23), transcript variant 4, 200 uL, >10^7 TU/mL
		200 µl / $2,050.00
		OriGene Technologies, Inc.

RC230652L1V	Lenti ORF particles, CDH23 (Myc-DDK-tagged)-Human cadherin-related 23 (CDH23), transcript variant 6, 200 uL, >10^7 TU/mL
		200 µl / $2,130.00
		OriGene Technologies, Inc.

RC230644L1V	Lenti ORF particles, CDH23 (Myc-DDK-tagged)-Human cadherin-related 23 (CDH23), transcript variant 7, 200 uL, >10^7 TU/mL
		200 µl / $2,070.00
		OriGene Technologies, Inc.

16 products - FILTER YOUR RESULTS!

Antibodies (see all»)

Kits (see all»)

Antigens

Lysates (see all»)

Other life-science products