SA6049 SETD7 / SET9

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0.1 mg / $270.00
Delivery Time: 10 working days*
(*) valid for US customers only

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SETD7 / SET9

Product Description for SETD7 / SET9

SETD7 / SET9.
Presentation: Purified

Properties for SETD7 / SET9

Product Category Proteins & Growth Factors
Target Category
Quantity 0.1 mg
Synonyms H3-K4-HMTase SETD7, Histone H3-K4 methyltransferase SETD7, Histone-lysine N-methyltransferase SETD7, KIAA1717, KMT7, Lysine N-methyltransferase 7, SET domain-containing protein 7, SET7, SET7/9
Presentation Purified
Molecular weight 40.7 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q8WTS6
Purity > 95 % by SDS-PAGE
Background SET 7/9 is a histone methyltransferase (HMTase) that transfers methyl groups to Lys4 of histone H3, in complex with S-adenosyl-L-methionine (AdoMet). The methylation of lysine residues of histones plays a critical role in the regulation of chromatin structure and gene expression. Acetylation, phosphorylation and methylation of the amino-terminal tails of histone are thought to be involved in the regulation of chromatin structure and function. The enzymes identified in the methylation of specific lysine residue on histones belong to the SET family with just one exception. SET 7/9, unlike most other SET proteins, is exclusively a mono-methylase.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings
  1. Bing xiao. et al(2003) Nature 421(50)652-656.
  2. Taewoo Kwon. et al(2003) EMBO 22(2) 292-303.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human SET7/9, was cloned into an E. coli expression vector and was purified to apparent homogeneity by using conventional column chromatography techniques.
AA Sequence:
MDSDDEMVEE AVEGHLDDDG LPHGFCTVTY SSTDRFEGNF VHGEKNGRGK FFFFDGSTLE GYYVDDALQG QGVYTYEDGG VLQGTYVDGE LNGPAQEYDT DGRLIFKGQY KDNIRHGVCW IYYPDGGSLV GEVNEDGEMT GEKIAYVYPD ERTALYGKFI DGEMIEGKLA TLMSTEEGRP HFELMPGNSV YHFDKSTSSC ISTNALLPDP YESERVYVAE SLISSAGEGL FSKVAVGPNT VMSFYNGVRI THQEVDSRDW ALNGNTLSLD EETVIDVPEP YNHVSKYCAS LGHKANHSFT PNCIYDMFVH PRFGPIKCIR TLRAVEADEE LTVAYGYDHS PPGKSGPEAP EWYQVELKAF QATQQK
Molecular weight:
(366 amino acids)
Format
Buffer System:
50 mM Tris-HCl buffer (pH7.5) 0.2M NaCl, 5mM DTT, 20% glycerol
Purity:
>95% by SDS-PAGE
State:
Liquid
Purified
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