Product Description for Apolipoprotein E / Apo E
Apolipoprotein E / Apo E.
Presentation: Purified
Presentation: Purified
Properties for Apolipoprotein E / Apo E
| Product Category | Proteins & Growth Factors |
|---|---|
| Target Category | |
| Quantity | 50 µg |
| Synonyms | Apo-E, ApoE |
| Presentation | Purified |
| Source | Plasma |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 95 % pure by SDS-PAGE. |
| Add. information | Centrifuge before opening to ensure complete recovery of vial contents. |
| Background | Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition. |
| Caution | All human source materials have tested negative for HIV 1, HIV 2, anti-HCV, anti-HBc antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious. |
| Concentration | 0.733 mg/ml (OD280 nm, E0.1% = 1.0) |
| Storage | Store the antigen at -20°C. Avoid multiple freeze/thaw cycles. Shelf life: one year from despatch. |
| Source | Very Low Density Lipoprotein (VLDL) from Human Plasma |
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