Product Description for MEKK5 / ASK1
anti MEKK5 / ASK1.
Properties: control peptide
Presentation: Purified
Properties: control peptide
Presentation: Purified
Properties for MEKK5 / ASK1
| Product Category | Control Peptides |
|---|---|
| Target Category | |
| Quantity | 50 µg |
| Synonyms | Apoptosis signal-regulating kinase 1, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, Mitogen-activated protein kinase kinase kinase 5 |
| Presentation | Purified |
| Clonality | Polyclonal |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Polyclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Add. information | Peptide MW: 1258 daltons. Peptide Sequence: acetyl-A-T-R-G-R-G-S-pS-V-G-G-G-amide. Purity: > 95% specific peptide. |
| Application | Intended for use as a control peptide when used with Anti-ASK1 to block specific interaction of Anti-ASK1 with ASK1. Control peptide should be used at 1.0 µg per 1.0 µl of antiserum in per assay. |
| Background | Mitogen activated protein (MAP) kinase cascades are activated in response to various extracellular stimuli including cytokines, growth factors and environmental stresses. A novel MAP kinase kinase kinase (MAPKKK) was recently identified and designated ASK1 (for apoptosis signal-regulating kinase 1). ASK1 activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activate c-Jun N terminal kinase (JNK) and p38 MAP kinase, respectively. ASK1 is activated by TNFR and Fas through the interaction with members of the TRAF family and Fas associated protein Daxx. Overexpression of ASK1 induces apoptotic cell death, and a catalytically inactive form of ASK1 inhibits TNF alpha-induced apoptosis. ASK1 is expressed in variety of human and mouse tissues. |
| Concentration | 1 mg/ml (by weight) |
| Storage | Store vial at -20°C or below prior to opening. Dilute only prior to immediate use. Aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Shelf life: One year from despatch. |
| Format |
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| Gene ID | 4217 |
Accessory Products
Recommended Secondary Antibodies for MEKK5 / ASK1 (0 products)
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