Product Description for COL4A3BP
anti COL4A3BP.
Properties: Control Peptide
Presentation: Purified
Properties: Control Peptide
Presentation: Purified
Properties for COL4A3BP
| Product Category | Control Peptides |
|---|---|
| Quantity | 50 µg |
| Synonyms | CERT, Ceramide transfer protein, Collagen type IV alpha-3-binding protein, GPBP, Goodpasture antigen-binding protein, STARD11, START domain-containing protein 11, StAR-related lipid transfer protein 11, StARD11, hCERT |
| Presentation | Purified |
| Clonality | Polyclonal |
| Isotype | IgG |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Polyclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Application | Western blot. Positive control: Ovary |
| Background | CERT mediates the ATP-dependent ER-to-Golgi transfer of ceramide in a non-vesicular manner. The biosynthesis of lipids involves steps that occur in different intracellular compartments. The movement of lipids within these compartments is important in lipid-mediated signalling. Human CERT is identical to a splice variant of human Goodpasture antigen-binding protein (GPBP26). CERT contains a phosphoinositide-binding pleckstrin-homology (PH) domain (which targets CERT to the Golgi by binding phosphatidylinositol-4-phosphate (PtdIns4P)), a middle region, and a putative lipid-transfer-catalysing domain called START. CERT and CERTL can specifically extract ceramide from phospholipid bilayers in a START-domain-dependent manner. CERT interacts with ER membranes and specifically extracts ceramide. CERT catalyses both the specific extraction of ceramide from donor vesicles and its transfer to acceptor vesicles. CERT can associate with the Golgi in a PtdIns4P dependent manner. |
| Concentration | Lot specific |
| Storage | Store at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format |
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| Specificity |
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| Gene ID | 10087 |
Accessory Products
Recommended Secondary Antibodies for COL4A3BP (0 products)
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