Carboxy Methyl Lysine - AP00663PU-N

Product Description for Carboxy Methyl Lysine

Goat anti Carboxy Methyl Lysine.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Product Category	Primary Antibodies
Quantity	1 mg
Synonyms	CML, Carboxymethyl-lysine
Presentation	Aff - Purified
Applications	E, WB
Clonality	Polyclonal
Host	Goat
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Polyclonal Antibodies (de)

Immunogen	Immunogen: Carboxymethylated Keyhole Limpet Hemocyanin (CML-KLH). Prepared by the reaction of the protein with glyoxylic acid.
Add. information	Centrifuge before opening to ensure complete recovery of vial contents.
Application	Western Blot. ELISA: 1/4,000-1/20,000.
Background	Carboxymethyl Lysine is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy.
Concentration	0.82 mg/ml (OD280nm, E0.1% = 1.35)
Storage	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	Purification: CML-protein Sepharose Affinity Chromatography Buffer System: 75mM PBS, pH 7.2 containing 75mM Sodium chloride and 0.5mM EDTA Preservatives: 0.02% Sodium Azide State: Liquid purified IgG fraction Aff - Purified
Specificity	Specificity: This antibody specifically binds to Carboxy Methyl Lysine / CML modified proteins.

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