Product Description for GSK3 beta
GSK3 beta.
Presentation: Purified
Presentation: Purified
Properties for GSK3 beta
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | GSK-3 beta, GSK3B, Glycogen synthase kinase-3 beta |
| Presentation | Purified |
| Molecular weight | 47.5 kDa |
| Source | Insect cells |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | GSK3B, also known as glycogen synthase kise-3 beta, acts as a negative regulator in the hormol control of glucose homeostasis. Also, this protein has diverse functions as Wnt sigling and regulation of transcription factors and microtubules, by phosphorylating and ictivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Recombint human GSK3B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventiol chromatography techniques. |
| Concentration | 0.25 mg/ml (determined by absorbance at 280nm) |
| General Readings | Desai SS., et al. (2014) J. Biol. Chem. 289(9):5386-5398.Cheng DD., et al. (2014) Biochem. Biophys. Res. Commun. 443(2):598-603. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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