AM33022PU-N GBGT1 (Forssman antigen) antibody

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0.1 mg / $370.00
Delivery Time: 10 working days*
(*) valid for US customers only

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Rat anti Mouse GBGT1 33B12

AM33022PU-N

Product Description for GBGT1

Rat anti Mouse GBGT1 33B12.
Properties: (Forssman antigen)
Presentation: Purified
Product is tested for Frozen Sections.

Properties for GBGT1

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms 3-N-acetylgalactosaminyltransferase 1, Forssman glycolipid synthase-like protein, Globoside alpha-1
Presentation Purified
Reactivity Ms
Applications C
Clonality Monoclonal
Clone 33B12
Host Rat
Isotype IgG2c
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q8VI38
Immunogen:
The antibody 33B12 is a rat anti-Forrsman glycosphingolipid (FGL) antibody derived by fusing mouse myeloma cells with spleen cells from a rat immunized with Mouse mammary tumors.
GeneID:
227671
Property Forssman antigen
Application Immunohistochemistry on Frozen sections.
Background The Forssman glycolipid is a glycosylceramide possessing a neutral pentasaccharide head group, referred to as the Forssman antigen (Fa) and is a member of the globoseries glycolipid family.
Fa has been identified in a number of mammals and exhibits heterogeneity with respect to developmental and cell-type expression among species. Some studies have reported the presence of the Fa in certain human embryonic and tumor cells.
The majority of human individuals have undetectable levels of Fa.
Gastric and colonic tumors from Fa-negative patients, however, contained relatively high levels of Fa. Moreover, compared with normal lung tissue, many lung cancers contained elevated levels of Fa.
These observations arouse interest in Fa for a possible role as a human tumor antigen.
Concentration 1.0 mg/ml
General Readings
  1. Sonnenberg A, van Balen P, Hengeveld T, Kolvenbag GJ, Van Hoeven RP, Hilgers J. Monoclonal antibodies detecting different epitopes on the Forssman glycolipid hapten. J Immunol. 1986 Aug 15;137(4):1264-9. PubMed PMID: 2426359.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Buffer System:
PBS
Preservatives:
0.09% Sodium Azide
State:
Liquid purified Ig fraction
Purified
Species Reactivity
Species reactivity (tested):
Mouse.
Specificity
Specificity:
Clone 33B12 and 117C9 detect overlapping epitopes on the Forssman glycolipid hapten (GalNA1- c3aG alNAcD1 -3GalaI-4GalB1-4GlcBl-lCer).
Clone 33B12 reacts with the terminal sugar sequence GalNAcd-3GalNAc and is specific for Forssman antigen.

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