Product Description for CD5
CD5.
Presentation: Purified
Presentation: Purified
Properties for CD5
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | CD5, LEU1, Lymphocyte antigen T1/Leu-1, T-cell surface glycoprotein CD5 |
| Presentation | Purified |
| Molecular weight | 41.0 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 80 % by SDS - PAGE |
| Background | CD5 is a good immunohistochemical marker for T-cells, although not as sensitive as CD3. About 76% of T-cell neoplasms are reported to express CD5, and it is also found in chronic lymphocytic leukemia, hairy cell leukemia, and mantle cell lymphoma cells. It is commonly lost in cutaneous T-cell lymphoma, and its absence can be used as an indicator of malignancy in this condition. The absence of CD5 in T cell acute lymphoblastic leukemia, while relatively rare, is associated with a poor prognosis. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Berland R. et al. (2002) Annu. Rev. Immunol. 20:253–300.Osman N. et al. (1992) Eur. J. Immunol. 22:2995–3000. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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