TNFRSF14 / HVEM (39-202, His-tag) - AR51263PU-S

Product Description for TNFRSF14 / HVEM

TNFRSF14 / HVEM.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	HVEA, Herpesvirus entry mediator A, TR2, Tumor necrosis factor receptor superfamily member 14, Tumor necrosis factor receptor-like 2
Presentation	Purified
Molecular weight	19.7 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q92956
Purity	> 85 % by SDS - PAGE
Background	TNFRSF14, as known as herpesvirus entry mediator (HVEM), is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Montgomery RI. et al. (1996) Cell. 87:427-436. Kwon BS. et al. (1997) J Biol Chem. 272:14272-14276.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human TNFRSF14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSLPSCKED EYPVGSECCP KCSPGYRVKE ACGELTGTVC EPCPPGTYIA HLNGLSKCLQ CQMCDPAMGL RASRNCSRTE NAVCGCSPGH FCIVQDGDHC AACRAYATSS PGQRVQKGGT ESQDTLCQNC PPGTFSPNGT LEECQHQTKC SWLVTKAGAG TSSSHWV` Molecular weight: (187aa) confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl Purity: >85% by SDS - PAGE State: Liquid purified protein Purified