Product Description for HS3ST1 / 3OST
HS3ST1 / 3OST.
Presentation: Purified
Presentation: Purified
Properties for HS3ST1 / 3OST
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | 3-OST-1, 3OST1, Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1, Heparan sulfate glucosamine 3-O-sulfotransferase 1 |
| Presentation | Purified |
| Molecular weight | 36.2 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | Heparan sulfate glucosamine 3-O-sulfotransferase 1, also known as HS3ST1, is sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. This protein catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | Shworak N.W., et al. (1997) J. Biol. Chem. 272:28008-28019 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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