Product Description for Carboxypeptidase E
Carboxypeptidase E.
Presentation: Purified
Presentation: Purified
Properties for Carboxypeptidase E
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | CPE, Carboxypeptidase H, Enkephalin convertase, Prohormone-processing carboxypeptidase |
| Presentation | Purified |
| Molecular weight | 51.4 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but constitutively secreted proteins. Mutations in CPE are implicated in type II diabetes. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Chu,K.Y., et al. (2011) Islets 3 (4), 155-165Lee,T.K.,et al. (2011) J. Clin. Invest. 121 (3), 880-892 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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