AR50482PU-S Ephrin-B3 (28-226, His-tag)

Search for all "Ephrin-B3"

0.1 mg / $320.00
Delivery Time: 10 working days*
(*) valid for US customers only

Quick Overview

Ephrin-B3

Product Description for Ephrin-B3

Ephrin-B3.
Presentation: Purified

Properties for Ephrin-B3

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms EFNB3, ELK-L3, EPH-related receptor transmembrane ligand ELK-L3, EPH-related receptor tyrosine kinase ligand 8, EPLG8, LERK-8, LERK8
Presentation Purified
Molecular weight 24.6 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q15768
Purity > 90 % by SDS - PAGE
Background EFNB3, also known as ephrin-B3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to, and induce the collapse of, commissural axons/growth cones in vitro.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings
  1. Negrete O.A., et al. (2006) PLoS Pathog. 2:78-86
  2. Brückner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R. EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron. 1999 Mar;22(3):511-24. PubMed PMID: 10197531.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human EFNB3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMLSLEP VYWNSANKRF QAEGGYVLYP QIGDRLDLLC PRARPPGPHS SPNYEFYKLY LVGGAQGRRC EAPPAPNLLL TCDRPDLDLR FTIKFQEYSP NLWGHEFRSH HDYYIIATSD GTREGLESLQ GGVCLTRGMK VLLRVGQSPR GGAVPRKPVS EMPMERDRGA AHSLEPGKEN LPGDPTSNAT SRGAEGPLPP PSMP
Molecular weight:
(224aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 2M urea
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
  • LinkedIn