Product Description for Leptin
Leptin.
Presentation: Purified
Presentation: Purified
Properties for Leptin
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | LEP, OB, OBS, Obese protein, Obesity factor |
| Presentation | Purified |
| Molecular weight | 16 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 95 % by SDS - PAGE |
| Background | Human leptin is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarily in the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated, resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes and infertility. The function of leptin in regulating appetite and metabolism, as well as the possibility of using leptin as a therapeutic agent, are currently under intense investigation. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| General Readings | Jeong KJ., et al. (1999) Appl Environ Microbiol. 65(7), 3027-32.Anini Y., et al. (2003) Diabetes. 52(2), 252-259.Hyogo H., et al. (2002) J. Biol. Chem. 277(37), 34117-34124. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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