Cyclooxygenase 1 - AP00117PU-N | acris-antibodies.com

Product Description for Cyclooxygenase 1

Rabbit anti Human, Mouse, Rat Cyclooxygenase 1.
Presentation: Aff - Purified
Product is tested for Immunoprecipitation, Western blot / Immunoblot.

Product Category	Primary Antibodies
Quantity	0.1 mg
Synonyms	COX-1, COX1, Cyclooxygenase-1, PGH synthase 1, PGHS-1, PTGS1, Prostaglandin G/H synthase 1, Prostaglandin H2 synthase 1, Prostaglandin-endoperoxide synthase 1
Presentation	Aff - Purified
Reactivity	Hu, Ms, Rt
Applications	IP, WB
Clonality	Polyclonal
Host	Rabbit
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Polyclonal Antibodies (de)

Immunogen	Swiss Prot Num: P23219 Immunogen: Synthetic peptide corresponding to residues surrounding amino acids 586 of mouse Cox-1 GeneID: 5742
Application	Western Blot: 1-4 μg/ml. Immunoprecipitation. Immunohistochemistry.
Background	COX proteins are membrane-associated heme proteins that have cyclooxygenase and peroxidase activities. These enzymes are targets of NSAID (Nonsteroidal anti-inflammatory drugs) such as aspirin. Prostaglandins (PGs) formed by the enzymatic activity of COX-1 are primarily involved in the regulation of homeostatic functions throughout the body, whereas PGs formed by COX-2 primarily mediate pain, fever, and inflammation. COX-1 is constitutively expressed, with particularly high expression in gastrointestinal tissues. COX-2 is induced by cytokines and mitogens and is likely to play a role in inflammatory diseases such as rheumatoid arthritis.
Concentration	0.2 mg/ml
Storage	Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	Purification: Immunoaffinity purified Buffer System: PBS containing 50% glycerol, 1% BSA, and 0.02% sodium azide State: Liquid purified Ig Aff - Purified
Specificity	Specificity: The antibody recognizes 70 kDa COX-1. It does not cross-react with COX-2. Species: Human, Mouse, Rat.
Gene ID	5742

Catalog No.	Species	Purity	Source
TP306436	Cyclooxygenase 1 (transcript variant 1)
	Human	> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.	HEK293 cells	20 µg / $748.00
				OriGene Technologies, Inc.

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