AR09416PU-L HRAS (1-186, His-tag)

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0.5 mg / $720.00
Delivery Time: 10 working days*
(*) valid for US customers only

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HRAS

AR09416PU-L

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  • AR09416PU-L

Product Description for HRAS

HRAS.
Presentation: Purified

Properties for HRAS

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms GTPase HRas, H-Ras, H-Ras-1, HRAS1, Ha-Ras, c-H-ras, p21ras, v-Ha-ras Harvey rat sarcoma viral oncogene homolog
Presentation Purified
Molecular weight kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P01112
Purity > 90 % by SDS - PAGE
Background HRAS, also known as GTPase HRas, belongs to the Ras family which function in signal transduction pathways. This protein can bind GTP and GDP, and it has intrinsic GTPase activity. HRAS undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. Defects in HRAS are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Ayllón V. et al. (2000) Mol Membr Biol. 17(2):65-73.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human HRAS protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHQYREQI KRVKDSDDVP MVLVGNKCDL AARTVESRQA QDLARSYGIP YIETSAKTRQ GVEDAFYTLV REIRQHKLRK LNPPDESGPG CMSCKCLEHH HHHH
Molecular weight:
(194 aa), confirmed by MALDI-TOF
Format
Buffer System:
Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 M NaCl
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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