discontinued

SP1310 MTBP (122-139) antibody

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Rabbit anti Human MTBP

SP1310

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  • SP1310

Product Description for MTBP

Rabbit anti Human MTBP.
Properties: (122-139)
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for MTBP

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Mdm2, Mdm2-binding protein, hMTBP
Presentation Aff - Purified
Reactivity Hu
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q96DY7
Immunogen:
Synthetic peptide corresponding to amino acids 122-139 of human MTBP
GeneID:
27085
Property 122-139
Application Western blot: 1 µg/ml; this antibody detects a band of approximately 104kD in K562 whole cell lystates.
Immunocytochemistry.
Background MDM2 is an important negative regulator of p53, which is over expressed in a range of human cancers. MTBP is expressed in a variety of normal tissues and is reported to bind to MDM2, inhibiting its effect on p53.
Concentration 0.5 mg/ml
General Readings
  1. Boyd MT, Vlatkovic N, Haines DS. A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2. J Biol Chem. 2000 Oct 13;275(41):31883-90. PubMed PMID: 10906133.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography
Buffer System:
PBS containing 0.02% Sodium Azide
State:
Liquid purified IgG
Aff - Purified
Specificity
Specificity:
This antibody recognises MDM2-binding protein (MTBP).
Species:
Human.

Accessory Products

Proteins and/or Positive Controls

Positive controls for MTBP (1 products)

Catalog No. Species Pres. Purity   Source  

MTBP overexpression lysate

MTBP overexpression lysate
0.1 mg / $295.00
  OriGene Technologies, Inc.
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