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TA309235 SNAP25 (C-term) antibody

Rabbit Anti-SNAP25 Antibody

See related secondary antibodies

Search for all "SNAP25"

0.1 ml / $405.00
Delivery Time: 5-7 working days*
(*) valid for US customers only

View Datasheet

Quick Overview

Rabbit anti Bovine, Canine, Chicken, Guinea Pig, Human, Mouse, Rat, Zebrafish SNAP25

TA309235

Product Description for SNAP25

Rabbit anti Bovine, Canine, Chicken, Guinea Pig, Human, Mouse, Rat, Zebrafish SNAP25.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for SNAP25

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms RIC4, SNAP, SNAP-25, SUP, Super Protein, Synaptosomal-associated 25 kDa protein, Synaptosomal-associated protein 25, ric-4
Presentation Aff - Purified
Reactivity Bov, Can, Chk, GP, Hu, Ms, non-Human Primates, Rt, Ze
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P60881
Immunogen:
Peptide corresponding to amino acid residues from the C-terminal region of rat SNAP25 conjugated to keyhole limpet hemocyanin (KLH).
GeneID:
25012
Property C-term
Application Western blot: 1/1,000.
Background SNAP25 (Synaptosomal associated protein of 25 kDa) is a presynaptic plasma membrane protein that is widely distributed throughout the brain and involved in the regulation of neurotransmitter release. Decreased levels of SNAP25 have been found in the brains of patients with Down Syndrome and Alzheimer's Disease (Greber et al.,1999). In addition, a significant reduction in the hippocampal expression of SNAP25 has also been found in patients with Schizophrenia (Fatemi et al., 2001).
General Readings
  1. Fatemi SH, Sidwell R, Kist D, Akhter P, Meltzer HY, Bailey K, et al. Differential expression of synaptosome-associated protein 25 kDa [SNAP-25] in hippocampi of neonatal mice following exposure to human influenza virus in utero. Brain Res. 1998 Jul 27;800(1):1-9. PubMed PMID: 9685568.
  2. Greber S, Cairns N, Lubec G, Fountoulakis M (1999) Decreased levels of the synaptosomal associated protein 25 in the brains of patients with Down Syndrome and Alzheimer's Disease. Electrophoresis 20 (4-5):928-34.
  3. Ando K, Kudo Y, Takahashi M. Negative regulation of neurotransmitter release by calpain: a possible involvement of specific SNAP-25 cleavage. J Neurochem. 2005 Aug;94(3):651-8. Epub 2005 Jun 30. PubMed PMID: 15992386.
  4. Fatemi SH, Earle JA, Stary JM, Lee S, Sedgwick J (2001) Altered levels of the synaptosomal associated protein Snap25 in hippocampus of patients with mood disorders and Schizophrenia. Neuroreport. 12(15): 3257-62.
Storage Store the antibody undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography.
Buffer System:
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% Glycerol.
State:
Liquid purified Ig fraction.
Aff - Purified
Species Reactivity
Species reactivity (expected):
Human, Bovine, Canine, Chicken, Mouse, Guinea Pig, Zebrafish and non-Human Primates.
Species reactivity (tested):
Rat.
Specificity
Specificity:
This antibody recognizes the ~25k SNAP25 protein.

Accessory Products

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Click here to see all secondary antibodies for SNAP25
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