AP50230PU-N RhoB (Center) antibody

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0.4 ml / $415.00
Delivery Time: 5-7 working days*
(*) valid for US customers only

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Rabbit anti Human RhoB

AP50230PU-N

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  • AP50230PU-N

Product Description for RhoB

Rabbit anti Human RhoB.
Properties: (Center)
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for RhoB

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms ARH6, ARHB, Rho cDNA clone 6, Rho-related GTP-binding protein RhoB
Presentation Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P62745
Immunogen:
KLH conjugated synthetic peptide between 103-137 amino acids from the Central region of human ARHB
GeneID:
388
Property Center
Add. information Molecular Weight: 22123 Da
Application ELISA: 1/1000.
Western blotting: 1/50 - 1/100.
Immunohistochemistry: 1/10 - 1/50.
Background ARHB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
Concentration lot specific
General Readings
  1. Adly, M.A., et al. J. Cutan. Pathol. 37(7):751-757(2010)
  2. Connolly, E.C., et al. Mol. Cancer Res. 8(5):691-700(2010)
  3. Zintzaras, E., et al. Am. J. Epidemiol. 171(8):851-858(2010)
  4. Kim, C.H., et al. Biochem. Biophys. Res. Commun. 391(2):1182-1186(2010)
  5. Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Saturated Ammonium Sulfate (SAS) precipitation
Buffer System:
PBS containing 0.09% (W/V) sodium azide as preservative
State:
Liquid purified Ig fraction
Purified
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody reacts to RhoB.
Gene ID 388

Accessory Products

Proteins and/or Positive Controls

Proteins for RhoB (3 products)

Catalog No. Species Pres. Purity   Source  

RhoB

RhoB Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $748.00
  OriGene Technologies, Inc.

RhoB (1-193, His-tag)

RhoB Human Purified > 90 % E. coli
0.25 mg / $1,070.00
  OriGene Technologies GmbH

RhoB (1-193, His-tag)

RhoB Human Purified > 90 % E. coli
50 µg / $400.00
  OriGene Technologies GmbH
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