Product Description for NOTCH2
Rabbit anti Human, Mouse, Rat NOTCH2.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections.
Properties for NOTCH2
| Product Category | Primary Antibodies |
|---|---|
| Target Category | |
| Quantity | 0.1 ml |
| Synonyms | Neurogenic locus notch homolog protein 2, Notch 2, hN2 |
| Presentation | Purified |
| Reactivity | Hu, Ms, Rt |
| Applications | E, P |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Shipping to | Europe, USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies, Inc. |
Datasheet Extract
| Immunogen |
|
|---|---|
| Application | ELISA: 1:2000-5000 IHC: 1:25-100 |
| Background | This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats; and an intracellular domain consisting of multiple; different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch sigling network is an evolutiorily conserved intercellular sigling pathway which regulates interactions between physically adjacent cells. In Drosophilia; notch interaction with its cell-bound ligands (delta; serrate) establishes an intercellular sigling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human; but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network; and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands; and may play a role in vascular; rel and hepatic development. Two transcript variants encoding different isoforms have been found for this gene. |
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Accessory Products
Recommended Secondary Antibodies for NOTCH2 (9 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | AP | Rb | E, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | Rb | E, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | Rb | E, ICC/IF, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | Rb | E, P, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | Rb | E, F, ICC/IF | |||
| OriGene Technologies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | Rb | F | |||
| OriGene Technologies GmbH | |||||||
| R1458C2 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1458C3 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1458C5 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
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