AP52627PU-N MBTPS2 (N-term) antibody

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0.4 ml / $415.00
Delivery Time: 5-7 working days*
(*) valid for US customers only

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Rabbit anti Human MBTPS2

AP52627PU-N

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  • AP52627PU-N

Product Description for MBTPS2

Rabbit anti Human MBTPS2.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for MBTPS2

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms Membrane-bound transcription factor site-2 protease, S2P, S2P endopeptidas, Site-2 protease, Sterol regulatory element-binding proteins intramembrane protease
Presentation Aff - Purified
Reactivity Hu
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O43462
Immunogen:
KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human MBTPS2
GeneID:
51360
Property N-term
Add. information Molecular Weight: 57444 Da
Application

ELISA: 1/1000.
Western Blot: 1/100-1/500.
Immunohistochemistry on Paraffin Sections: 1/10-1/50.

Background This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.
Concentration 0.5 mg/mL
General Readings Ming, A., et al. Pediatr Dermatol 26(4):427-431(2009)
Oeffner, F., et al. Am. J. Hum. Genet. 84(4):459-467(2009)
Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)
Shen, J., et al. J. Biol. Chem. 279(41):43046-43051(2004)
Lee, K., et al. Genes Dev. 16(4):452-466(2002)
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Protein A column, followed by peptide affinity purification
Buffer System:
PBS containing 0.09% (W/V) Sodium Azide as preservative
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody recognizes Human MBTPS2 (N-term).
Gene ID 51360

Accessory Products

Proteins and/or Positive Controls

Positive controls for MBTPS2 (1 products)

Catalog No. Species Pres. Purity   Source  

MBTPS2 overexpression lysate

MBTPS2 overexpression lysate
0.1 mg / $495.00
  OriGene Technologies, Inc.
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