AP22575PU-N MBD2 (15-29) antibody

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50 µg / $425.00
Delivery Time: 5-7 working days*
(*) valid for US customers only

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Goat anti Bat, Bovine, Canine, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat MBD2

AP22575PU-N

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Product Description for MBD2

Goat anti Bat, Bovine, Canine, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat MBD2.
Properties: (15-29)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Enzyme Immunoassay, Paraffin Sections.

Properties for MBD2

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms DMTase, Demethylase, Methyl-CpG-binding domain protein 2
Presentation Aff - Purified
Reactivity Bov, Bt, Can, Elephant, Eq, Hst, Hu, Mky, Ms, Por, Rb, Rt
Applications E, P, WB
Clonality Polyclonal
Host Goat
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9UBB5
Immunogen:
Synthetic peptide from an internal region of human MBD2
AA Sequence:
C-RNDPLNQNKGKPDLN
GeneID:
8932
Remarks:
Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum (100%); Xenopus (93%); Zebrafish (80%)
Property 15-29
Application ELISA: 1/64000.
Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
Western Blot.
Background DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters.
Concentration 0.5 mg/ml
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Immunoaffinity chromatography
Buffer System:
Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (expected):
Zebrafish
Species reactivity (tested):
Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Xenopus
Specificity
Specificity:
This antibody detects MBD2 (Internal).
It is expected to resognize isoform 1 (NP_003918.1) only.
Gene ID 8932

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