Product Description for LDHA
Rabbit anti Human, Mouse, Rat LDHA.
Presentation: Purified
Presentation: Purified
Properties for LDHA
| Product Category | Primary Antibodies |
|---|---|
| Target Category | |
| Quantity | 0.1 mg |
| Synonyms | Cell proliferation-inducing gene 19 protein, L-lactate dehydrogenase A chain, LDH muscle subunit, LDH-A, LDH-M, NY-REN-59, PIG19, Renal carcinoma antigen NY-REN-59 |
| Presentation | Purified |
| Reactivity | Hu, Ms, Rt |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Shipping to | Europe, USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies, Inc. |
Datasheet Extract
| Immunogen |
|
|---|---|
| Application | WB 1:500 - 1:2000 IHC 1:50- 1:200 |
| Background | Lactate dehydrogese (LDH) catalyzes the interconversion of pyruvate and DH to lactate and D+. When the oxygen supply is too low for mitochondrial ATP production, this reaction recycles DH generated in glycolysis to D+, which reenters glycolysis. The major form of LDH found in muscle cells is the A (LDHA) isozyme. The LDHA promoter contains HIF-1a binding sites. LDHA expression is induced under hypoxic conditions. During intensive and prolonged muscle exercise, lactate accumulates in muscle cells when the supply of oxygen does not meet demand. When oxygen levels return to normal, LDH converts lactate to pyruvate to generate ATP in the mitochondrial electron transport chain. |
| Format |
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Accessory Products
Proteins and/or Positive Controls
Proteins for LDHA (4 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| TP309378 |
LDHA (transcript variant 1) |
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|
Human |
> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
$748.00
|
|||
| OriGene Technologies, Inc. | |||||||
| TP720209 |
LDHA (transcript variant 2) |
||||||
|
Human |
> 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
10 µg /
$299.00
|
|||
| OriGene Technologies, Inc. | |||||||
| AR09387PU-L |
LDHA (1-332, His-tag) |
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|
Human | Purified | > 95 % by SDS - PAGE | E. coli |
0.5 mg /
$720.00
|
||
| OriGene Technologies GmbH | |||||||
| AR09387PU-N |
LDHA (1-332, His-tag) |
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|
Human | Purified | > 95 % by SDS - PAGE | E. coli |
0.1 mg /
$290.00
|
||
| OriGene Technologies GmbH | |||||||
Positive controls for LDHA (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| LY427601 |
LDHA overexpression lysate |
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0.1 mg /
$315.00
|
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| OriGene Technologies, Inc. | |||||||
| LY431321 |
LDHA overexpression lysate |
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0.1 mg /
$315.00
|
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| OriGene Technologies, Inc. | |||||||
Recommended Secondary Antibodies for LDHA (9 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
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|
Goat | AP | Rb | E, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | Biotin | Rb | E, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | FITC | Rb | E, ICC/IF, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | Rb | E, P, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | TRITC | Rb | E, F, ICC/IF | |||
| OriGene Technologies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
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|
Donkey | PE | Rb | F | |||
| OriGene Technologies GmbH | |||||||
| R1458C2 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1458C3 |
Rabbit IgG (H+L chain, adsorbed) antibody |
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|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1458C5 |
Rabbit IgG (H+L chain, adsorbed) antibody |
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|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||

