TA306585 DLGAP2 antibody

Rabbit Polyclonal SAPAP2 Antibody

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0.1 mg / $415.00
Delivery Time: 5-7 working days*
(*) valid for US customers only

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Rabbit anti Human, Mouse, Rat DLGAP2

TA306585

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  • TA306585
  • TA306585

Product Description for DLGAP2

Rabbit anti Human, Mouse, Rat DLGAP2.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for DLGAP2

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms DAP-2, DAP2, Disks large-associated protein 2, PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, SAPAP2
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9P1A6
Immunogen:
SAPAP2 antibody was raised against a 16 amino acid peptide from near the center of human SAPAP2.
GeneID:
9228
Add. information Blocking peptide available: AP30750CP-N
Application ELISA.
Western blot: 0.5 – 1 μg/ml.
Immunohistochemistry on paraffin sections.
Background SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP2 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. At least three isoforms of SAPAP2 are known to exist.
General Readings
  1. Takeuchi M, Hata Y, Hirao K, Toyoda A, Irie M, Takai Y. SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. J Biol Chem. 1997 May 2;272(18):11943-51. PubMed PMID: 9115257.
  2. Ranta S, Zhang Y, Ross B, Takkunen E, Hirvasniemi A, de la Chapelle A, et al. Positional cloning and characterisation of the human DLGAP2 gene and its exclusion in progressive epilepsy with mental retardation. Eur J Hum Genet. 2000 May;8(5):381-4. PubMed PMID: 10854099.
  3. Kindler S, Rehbein M, Classen B, Richter D, Böckers TM. Distinct spatiotemporal expression of SAPAP transcripts in the developing rat brain: a novel dendritically localized mRNA. Brain Res Mol Brain Res. 2004 Jul 5;126(1):14-21. PubMed PMID: 15207911.
  4. Bongiorno-Borbone L, Kadare G, Benfenati F, et al. FAK and PYK2 interact with SAP/PSD-95-associated protein-3. Biochem. Biophys. Res. Commun. 2005; 337:641-6.
Storage Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Peptide affinity chromatography
Buffer System:
PBS containing 0.02% sodium azide
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, mouse, rat
Specificity
Specificity:
This antibody detects SAPAP2. It will not cross-react with other SAPAP proteins.

Accessory Products

Proteins and/or Positive Controls

Positive controls for DLGAP2 (1 products)

Catalog No. Species Pres. Purity   Source  

DLGAP2 overexpression lysate

DLGAP2 overexpression lysate
0.1 mg / $495.00
  OriGene Technologies, Inc.
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