AP54862PU-N Complement factor I antibody

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0.1 mg / $450.00
Delivery Time: 10 working days*
(*) valid for US customers only

Quick Overview

Rabbit anti Human Complement factor I

Product Description for Complement factor I

Rabbit anti Human Complement factor I.
Presentation: Purified
Product is tested for Paraffin Sections, Frozen Sections, Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Complement factor I

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms AHUS3, C3B/C4B inactivator, C3BINA, C3b-INA, CFI, IF, KAF
Presentation Purified
Reactivity Hu
Applications C, E, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P05156
Immunogen:
Synthetic peptide derived from an internal domain of Human CFI
GeneID:
3426
Application

ELISA.
Western Blot: 1/200-1/2000.
Immunohistochemistry: 1/50-1/500.

Background Defects in CFI are a cause of susceptibility to hemolytic uremic syndrome atypical type 3 (AHUS3) [MIM:612923]. An atypical form of hemolytic uremic syndrome. It is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease. Note=Susceptibility to the development of atypical hemolytic uremic syndrome can be conferred by mutations in various components of or regulatory factors in the complement cascade system. Other genes may play a role in modifying the phenotype.
Defects in CFI are the cause of complement factor I deficiency (CFI deficiency) [MIM:610984]. CFI deficiency is an autosomal recessive condition associated with a propensity to pyogenic infections.
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography on Protein A
Buffer System:
0.1M Tris, 0.1M Glycine, 2% Sucrose
Preservatives:
None
State:
Lyophilized purified powder
Purified
Reconstitution:
Restore in distilled water.
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
Reacts with 65 kDa CFI protein.
Gene ID 3426

Accessory Products

Proteins and/or Positive Controls

Proteins for Complement factor I (1 products)

Catalog No. Species Pres. Purity   Source  

Complement factor I

Complement factor I Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $748.00
  OriGene Technologies, Inc.
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