AP50336PU-N BAG4 (C-term) antibody

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0.4 ml / $415.00
Delivery Time: 5-7 working days*
(*) valid for US customers only

Quick Overview

Rabbit anti Human BAG4

Product Description for BAG4

Rabbit anti Human BAG4.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for BAG4

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms BAG family molecular chaperone regulator 4, BAG-4, Bcl-2-associated athanogene 4, SODD, Silencer of death domains
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O95429
Immunogen:
KLH conjugated synthetic peptide between 380-409 amino acids from the C-terminal region of human BAG4
GeneID:
9530
Property C-term
Add. information Molecular Weight: 49594 Da
Application ELISA: 1/1000.
Western blotting: 1/100 - 1/500.
Background BAG4 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost.
Concentration lot specific
General Readings
  1. Bailey, S.D., et al. Diabetes Care (2010)
  2. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  3. Tao, H.F., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 15(3):501-505(2007)
  4. Riley, B.M., et al. Am. J. Med. Genet. A 143A (8), 846-852 (2007)
  5. Yang, Z.Q., et al. Cancer Res. 66(24):11632-11643(2006)
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography on Protein A
Buffer System:
PBS containing 0.09% (W/V) sodium azide as preservative
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody reacts to BAG4.
Gene ID 9530

Accessory Products

Proteins and/or Positive Controls

Proteins for BAG4 (1 products)

Catalog No. Species Pres. Purity   Source  

BAG4

BAG4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $748.00
  OriGene Technologies, Inc.

Positive controls for BAG4 (1 products)

Catalog No. Species Pres. Purity   Source  

BAG4 overexpression lysate

BAG4 overexpression lysate
0.1 mg / $295.00
  OriGene Technologies, Inc.
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